Clinical Study Of Traditional Chinese Medicine Intervention Scheme For Idiopathic Olfactory Dysfunction

Objective:The study was a randomized controlled trial,which aimed to observe the curative effect of acupuncture of sphenopalatine ganglion combined with oral Chinese medicine and olfaction training in the treatment of idiopathic olfaction dysfunction.Methods:55 patients with idiopathic olfactory disorder of Qi deficiency and blood stasis who met the inclusion criteria were randomly divided into experimental group(28 cases)and control group(27 cases),and during the treatment,there was 1 case of shedding due to needle fainting in the experimental group and 1 case of shedding due to non-adherence to medication in the control group,finally 53 cases were completed.The experimental group was given sphenopalatine ganglion acupuncture,oral Chinese medicine Yiqi Huoxue Fuxiu decoction combined with olfactory training;the control group was given fluticasone propionate nasal spray(Flixonase),mecobalamine tablet oral combined with olfactory training.Both groups were treated for 8 weeks,and followed up 1 month after treatment.The changes of VAS score,score of olfactory identification screening test and quality of life scale for olfactory disorders before and after treatment were observed in the two groups.SPSS25.0 software was used to analyzing the clinical efficacy.Results:(1)Baseline data analysis: Sex,age,disease time,VAS score,olfactory identification screening test score and QOD scale score before treatment were comparable between the experimental group and the control group(P>0.05).(2)Research data analysis:After treatment,the scores of both groups decreased compared with those before treatment,the difference was statistically significant(P<0.05).The improvement of VAS score,olfactory recognition screening test score and QOD-NS scale score in experimental group was better than control group(P<0.05),but there was no significant difference in QOD-VAS scale score between the two groups(P>0.05).(3)Efficiency analysis:The effective rate of experimental group and control group was statistically different(P<0.05),and the total effective rate of experimental group was 55.56%,which one person was cured,14 were effective and 12 were invalidthe,total effective rate of control group was26.92%,which 1 person was effective,6 persons were effective and 19 were invalid.(4)Follow-up effect analysis:At the follow-up of 1 month after treatment,there was no significant difference in VAS score of the experimental group at the follow-up compared with the end of treatment(P>0.05),there was no significant difference in VAS score of the control group at the follow-up compared with the end of treatment(P>0.05),and there was no significant difference in VAS score chane between the two groups(P>0.05).Conclusion:Acupuncture of sphenopalatine ganglion,oral Chinese medicine Yiqi Huoxue Fuxiang Decoction combined with olfactory training have obvious advantages compared with Fushuliang nasal spray and mecobalamine tablet combined with olfactory training in the treatment of idiopathic olfactory disorder(Qi deficiency and blood circulation syndrome),providing reference for the comprehensive treatment of TCM for idiopathic olfactory disorder.