The Efficacy Of Five-tone Therapy Combined With Modified Liuzijue On Post-Stroke Depression

Objective: To explore the clinical therapeutic effect of five-tone therapy,modified Liuzijue,five-tone therapy combined with modified Liuzijue on patients with post-stroke depression(PSD)of liver-qi stagnation type,observe the changes of depression status,TCM syndrome score,neurological function and activities of daily living before and after the intervention,and provide a safe and effective method without side effects for clinical treatment of such patients.Methods: From November 2021 to December 2022,87 patients with liver qi stagnation type PSD hospitalized in the Rehabilitation Department of the Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine were selected and randomly divided into three groups with 29 patients in each group.The five-tone treatment group was treated with five element jue-tone music intervention,the Liuzijue treatment group was treated with modified Liuzijue training,and the combined group was treated with five element jue-tone music combined with modified Liuzijue.The three groups were treated for 30 minutes/time,1 time/day,5 times/week,and a course of treatment lasted for 4 weeks.Hamilton Depression Rating Scale(HAMD-17),National Institute of Health stroke scale(NIHSS),Traditional Chinese Medicine Syndrome Integration Scale,and Modified Barthel Index(MBI)were used to evaluate before and after treatment.The total effective rate of the five-tone group was 80.77%,the Liuzijue group was 84.62%,and the combined group was 92.31%.After statistical analysis,the difference between the five-tone group and the Liuzijue group was not statistically significant(P>0.05);There were significant differences between the five-tone group and the combination group,and between the Liuzijue group and the combination group(P<0.05).It suggests that the combined group is better than the other two groups in improving the depression of PSD patients.Result: There was no significant difference in the general data,HAMD-17,TCM syndrome score,NIHSS and MBI score of the three groups of patients before treatment(P>0.05).After treatment,the HAMD-17,TCM syndrome score,NIHSS and MBI scores of the three groups were significantly different from those before treatment(P < 0.001).After treatment,there was no significant difference in HAMD-17,TCM syndrome score and NIHSS score between the five-tone group and the Liuzijue group(P>0.05).There were statistically significant differences in HAMD-17,TCM syndrome score and NIHSS score between the five-tone group and the combination group,the Liuzijue group and the combination group(P<0.05).It shows that the combined treatment is superior to the simple use of five-tone therapy or modified Liuzijue training in improving the depression status,TCM syndrome score,neurological function.After treatment,the MBI scores of the three groups were significantly different(P<0.05).In terms of improving activities of daily living,the curative effect of the Liuzijue group is better than that of the five-tone group,while the combined group is also better than that of the five-tone group and the Liuzijue group.Conclusion: 1.The five-tone combined modified Liuzijue can effectively improve the depression,liver-qi stagnation,neurological function and activities of daily life of PSD patients.The combined intervention can give full play to the advantages of both five-tone therapy and modified Liuzijue,and play a synergistic effect.Within the same treatment time,the patients’ psychological and physiological status can improve the most significant quality,which is better than the simple five-tone therapy and modified Liuzijue training.2.The five-tone therapy and modified Liuzijue can effectively improve the depression,liver-qi stagnation,neurological function and activities of daily life of PSD patients.In terms of improving the activities of daily life,the modified Liuzijue is better than the five-tone therapy.