| Objective: Susceptibility weighted imaging(SWI)was used to analyze the factors affecting the short-term prognosis of patients with acute ischemic stroke(AIS).To explore the predictive value of cerebral microbleeds(CMBs)and asymmetrical cortical vein sign(ACVS)for the short-term prognosis of AIS patients,evaluate whether CMBs and ACVS can be used as imaging markers of good or bad short-term prognosis of patients with AIS,and provide imaging basis for clinical intervention and treatment of patients with AIS.Methods: A retrospective analysis was conducted on patients with AIS admitted to the Second Clinical Medical Faculty of Inner Mongolia University for Nationalities from January 1,2021,to August 31,2022.All patients received the same treatment(dual antiplatelet agents)and management protocol after admission according to the Chinese Guidelines for the Diagnosis and Treatment of Acute Stroke 2018,and these patients did not have complications during admission or at discharge and were discharged on the 14 th day after admission.Patients meeting the requirements were strictly screened according to the established inclusion and exclusion criteria,and demographic data,clinical data and imaging data of enrolled patients were collected.After the demographic data and clinical data were covered,imaging data of all patients were analyzed and recorded respectively.According to the short-term prognosis criteria,the above patients were divided into the group with good and poor short-term prognosis.Univariate analysis was conducted to exclude the relevant factors with no significant statistical significance,and the influencing factors with statistical differences were incorporated into binary Logistic regression analysis to analyze the relevant factors affecting the short-term prognosis of AIS,and to determine whether CMBs and ACVS shown by SWI sequence can be independent predictors of poor prognosis of AIS.Results: A total of 171 patients were enrolled,including 72 patients with good short-term prognosis and 99 patients with poor short-term prognosis.Of these patients,66 patients were positive for CMBs and 88 were positive for ACVS,including 9 patients with ACVS-2,27 patients with ACVS-1,35 patients with ACVS 1,17 patients with ACVS 2,and patients with ACVS 3 were not observed in this study.The comparative analysis between the two groups suggested that patients with CMBs in the poor prognosis group were greater than those in the good prognosis group,and the number of CMBs was significantly higher than that in the good prognosis group(P < 0.001).In addition,the short-term prognosis of patients with AIS was also related to discharged NIHSS and different grades of ACVS,and high score of discharged NIHSS and positive ACVS reflected poor short-time prognosis of AIS.All the above differences were statistically significant(P < 0.001).Multivariate regression analysis suggested that discharged NIHSS,CMBs and ACVS were independently correlated with the short-term poor prognosis of AIS,and the number of CMBs could not be used as an independent predictor of the short-term poor prognosis of AIS.ACVS grade 1 could better predict the short-term prognosis of AIS than other grades of ACVS.Conclusion: Discharged NIHSS,CMBs and ACVS were influential factors for the short-term prognosis of AIS,as well as independent predictors of the poor short-term prognosis of AIS.High discharge NIHSS score,positive CMBs and positive ACVS indicated the poor short-term prognosis of AIS.The number of CMBs was an influential factor for the short-term prognosis of AIS,but not an independent predictor for the poor short-term prognosis of AIS.The cortical veins on the ischemic side of AIS can be increased or decreased,ACVS grade 1 has a more reliable predictive value for short-term prognosis,and the classification of ACVS can more accurately predict the short-term prognosis of AIS. |
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