| Objectiv: To observe the clinical efficacy of diarrhoea prescription combined with bifidobacterium triple live bacteria in the treatment of IBSD,explore the advantages and characteristics of traditional Chinese and Western medicines,observe whether the treatment method of integrated Chinese and Western medicine is better than single traditional Chinese medicine or Western medicine treatment,and explore whether the addition of liver thinning and qi and moisture to Chinese medicine formulas can help the treatment of IBS-D.Content: This topic treats IBS-D in Western medicine based on the theory of diarrhoea in traditional Chinese medicine,takes into account the physical and mental treatment of emotional problems,and adds drugs to relieve pain and diarrhea,in order to confirm the rationality of the treatment of IBS-D based on the principles of inhibiting the liver and supporting the spleen,thinning the liver and regulating qi,and relieving moisture and diarrhea.In addition,the triple live bacteria that improve the intestinal flora environment were selected as the treatment method of Western medicine,and the combination of Chinese and Western treatment was compared with a single Chinese medicine or Western medicine treatment.In clinical trials,the observation of the changes of various symptoms,fecal traits and anxiety states of liver depression and spleen deficiency diarrhea in traditional Chinese medicine was used as the evaluation standard for efficacy.Detailed records of changes in the patient’s symptoms.In terms of data analysis,SPSS27.0 was selected as the data analysis tool,and the normal test was performed for the measurement data,and the normal distribution data was expressed as mean ± standard deviation.Nonnormal distribution data are represented by the median[M(P25,P75)].Through this project,the clinical efficacy of IBS-D under combination therapy mode was observed and studied,and the respective therapeutic advantages of Chinese and Western medicine and the advantages of combination therapy were demonstrated.Methods: From December 2021 to December 2022,patients who attended the Second Department of Gastroenterology of the Affiliated Hospital of Shandong University of Traditional Chinese Medicine and the Department of Gastroenterology of Shandong Provincial Hospital of Integrated Traditional Chinese and Western Medicine were selected,and 90 IBS-D patients who met the criteria were selected as the research subjects,and were divided into three groups: traditional Chinese medicine group,western medicine group and experimental group(combination of traditional Chinese and western medicine)by random grouping method,corresponding to the treatment plan of traditional Chinese medicine,western medicine and combination of traditional Chinese and western medicine,and the relevant indicators of patients were recorded in the form of questionnaires before treatment and on the 30 th day of treatment,and finally statistical analysis with data.Result:(1)On the 30 th day of treatment,there were significant statistical differences in TCM syndrome scores,SAS anxiety scale and fecal traits in the three groups(P<0.01);(2)The effective rate of the comparative test group(Chinese and Western medicine experimental group)was 93%> the effective rate of the Chinese medicine group(86%)> the Western medicine group(83%);(3)The Western medicine group had more advantages than the Chinese medicine group in the treatment of diarrhea frequency and poor feeding,while the Chinese medicine group was better than the Western medicine group in terms of abdominal pain,irritability,chest and flank fullness and other TCM symptoms,and the experimental group was weaker than the Chinese medicine group but better than the Western medicine group in terms of improvement of fecal properties;(4)Compared with the 0th day of treatment,the difference in TCM syndrome score,SAS score and fecal traits was statistically significant(P<0.01).Conclusion : All three groups were effective in the treatment of IBSD,while the experimental group had the highest effective rate and the best effect.The western medicine group had a greater advantage in antidiarrheal than traditional Chinese medicine in a short period of time,which could significantly reduce the frequency of diarrhea and have significant curative effects.The Chinese medicine group had a better effect on the improvement of TCM symptoms,and the addition of drugs to relieve liver and qi may help relieve irritability and irritability,and the addition of dampness relieving drugs may play a role in the fatigue or spleen of wet and evil spirits.The comprehensive effect of the combination of traditional Chinese and Western medicine combined with bifidobacterium is better than that of single traditional Chinese medicine or western medical method,which significantly improves the patient’s syndrome points and anxiety state,and the effect on the change of fecal traits is also obvious,which can improve the clinical efficacy of the treatment of diarrhea-type irritable bowel syndrome. |
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