Study On The Prescription Medication Law Of Coronary Heart Disease(Chest Obstruction And Heart Pain) Treated By Classic Prescriptions In Ancient Literature

Objective:Based on the comprehensive excavation of the ancient Chinese medicine books from Mawangdui to the Republic of China recorded in the Encyclopaedia Of Traditional Chinese Medicine,this paper analyzes and summarizes the medication rules of ancient doctors in treating coronary heart disease(chest obstruction and heartache)with classic prescriptions,and provides a reference for the prevention and treatment of coronary heart disease with classic prescriptions in clinic today.Methods:Based on the Encyclopaedia Of Traditional Chinese Medicine,the ancient Chinese medicine books from Mawangdui to the Republic of China were comprehensively excavated,and the classic prescriptions were collected to treat coronary heart disease(chest obstruction and heartache).By analyzing the frequency and frequency of high-frequency classic prescriptions,as well as the frequency and frequency of drugs’ taste and efficacy,and combining with the original text and clinical practice,this paper summarizes the law of adding and subtracting drugs in treating coronary heart disease(chest obstruction and heartache)by using classic prescriptions in ancient Chinese medicine literature.Results:1.Distribution of prescriptions:1014 prescriptions were initially screened,and after the second screening,the prescriptions that were not modified by classic prescriptions were removed,and finally 249 prescriptions were included.Among the 249 prescriptions,there are 38 classic prescriptions,which are from 93 ancient books.These ancient books are distributed in Han,Jin,Tang,Song,Jin,Yuan,Ming,Qing,and Republic of China,among which the Qing Dynasty is the most widely distributed.1 ancient book of the Han dynasty,1 square;There are 2 ancient books in Wei,Jin,Southern,and Northern Dynasties and 3 prescriptions.There are 2 ancient books in Tang Dynasty and 7 prescriptions.There are 9 ancient books in Song Dynasty and 50 prescriptions.1 ancient book in Jin Dynasty,1 Fang;There are 3 ancient books in Yuan Dynasty and 4 prescriptions.There are 18 ancient books in Ming Dynasty,with 49 prescriptions;There are 55 ancient books in Qing Dynasty with 115 prescriptions.2.Usage of classical prescriptions:249 modified classical prescriptions were finally included,involving 38 classical prescriptions,and prescriptions with pungent and warm effects were dominant,among which Guizhi Decoction and Lizhong Decoction were the most frequently used.There are 17 classic prescriptions with frequency>5,including Lizhong Decoction 29 times,Guizhi Decoction 29 times,Gualou Xiabai Banxia Decoction 25 times,Sini Decoction 25 times,Guizhi Shengjiang Zhishi Decoction 18 times,Ling Gui Zhu Gan Decoction 18 times,Banxia Houpu Decoction 17 times,Xiao Banxia Jia Fuling Decoction 16 times,Zhishi Xiebai Guizhi Decoction15 times,Danggui Shaoyao Decoction 14 times,Xiao Chaihu Decoction 12 times,Ju Zhi Jiang Decoction 11 times,Wutou Chishizhi Decoction 10 times,Fuling Xingren Gancao Decoction 7 times,Xuanfuhua Decoction 7 times,Huangqin Decoction 6 times,and Xiao Xianxiong Decoction 6 times.3.Usage of high-frequency classical prescriptions of traditional Chinese medicine and drugs:statistics were made on the modified classical prescriptions with the frequency of use>5 and Gualou Xiebai Bai jiu Decoction.Gualou Xiebai Baijiu Decoction is mostly compatible with qi-regulating drugs and exterior-relieving drugs;Gualou Xiebai Banxia Decoction is more compatible with Poria cocos and ginger,and more exterior-relieving drugs,expectorant,anti tussive and antiasthmatic drugs and qi-regulating drugs are used.Zhishi Xiebai Guizhi Decoction is mostly combined with Pinellia ternate,ginger,and dried tangerine peel,and expectorant,antitussive,and antiasthmatic drugs and dampness-removing and dampness-removing drugs are mostly used.Lizhong Decoction is mostly combined with aconite and Poria cocos,and it is mostly used to warm the interior and relieve exterior syndrome;Ju Zhi Jiang Decoction is mostly combined with Radix Aucklandiae,Radix Glycyrrhizae,and Rhizoma Pinelliae,and it is mostly used for phlegm-resolving,cough-relieving and asthma-relieving drugs and tonic drugs.Fuling Xingren Gancao Decoction is more compatible with ginger,and more qi-regulating drugs,phlegm-resolving,cough-relieving,and asthma-relieving drugs are used;Wutou Chishizhi Decoction is mostly combined with Evodia rutaecarpa,wine and cassia twig,and are mostly used for warming the interior and relieving exterior symptoms;Sini Decoction is mostly compatible with Atractylodes macrocephala and Ginseng,and mostly uses tonics and tonics.Guizhi Shengjiang Zhishi Decoction is mostly combined with Pinellia ternata and Poria,and it is mostly used for phlegm-resolving,cough-relieving,and asthma-relieving drugs and tonic drugs.Ling Gui Zhu Gan Decoction is mostly combined with Pericarpium Citri Tangerine and Pinellia ternata and is mainly used for regulating qi,resolving phlegm,and relieving cough and asthma.Guizhi Decoction is mostly combined with angelica,Evodia rutaecarpa,ginseng,and dried ginger,and is mostly used for warming the interior and tonifying the deficiency;Xiao Chaihu Decoction is more compatible with Paeonia lactiflora and Coptis chinensis,and more heat-clearing drugs and tonic drugs are used;Huangqin Decoction is more compatible with ginger and Bupleurum,and more exterior-relieving drugs and heat-clearing drugs are used;Xiao Xianxiong Decoction is mostly combined with Platycodon grandiflorum and Fructus Aurantii Immaturus,and is mainly used for regulating qi,resolving phlegm,relieving cough and asthma.Danggui Shaoyao Decoction is mostly combined with Glycyrrhiza uralensis Fisch and Ginseng Radix,and mostly used tonics and tonics.Xuanfuhua Decoction is mostly combined with Radix Curcumae and Radix Angelicae Sinensis,and mostly used qi-regulating drugs and tonic drugs;Banxia Houpu Decoction is mostly combined with Glycyrrhiza uralensis Fisch,Fructus aurantii,Paeonia lactiflora and Pericarpium Citri Tangerinae,and mostly used tonics and qi-regulating drugs;Xiao Banxia Jia Fuling Decoction is more compatible with Fructus Aurantii Immaturus and Ramulus Cinnamomi,and more qi-regulating drugs,phlegm-resolving,cough-relieving and asthma-relieving drugs are used.4.Distribution of drug properties and meridian tropismof high-frequency classic prescriptions:statistics were made on the modified classical prescriptions with the frequency of use>5 and Gualou Xiebai Bai jiu Decoction.In terms of drug properties,Gualoulou Xiebai Bai jiu Decoction,Gualou Xiebai Banxia Decoction,Zhishi Xiebai Guizhi Decoction,Lizhong Decoction,Ju Zhi Jiang Decoction,Fuling Xingren Gancao Decoction,Wutou Chishizhi Decoction,Sini Decoction,Guizhi Shengjiang Zhishi Decoction,Ling Gui Zhu Gan Decoction,Guizhi Decoction,Danggui Shaoyao Decoction,Xuanfuhua Decoction,Banxia Houpu Decoction,and Xiao Banxia Jia Fuling Decoction are mostly used as warming drugs,Xiao Chaihu Decoction,Huangqin Decoction,and Xiao Xianxiong Decoction are mostly used with mild cold drugs.Among the 18 modified prescriptions,Gualou Xiebai Bai jiu Decoction and Xiao Chaihu Decoction are mostly bitter.The pungent taste is the most commonly used medicine in other prescriptions.In terms of meridian tropism,among the 18 classic prescriptions,the flavored drugs of Wutou Chishizhi Decoction mostly belong to the lung,stomach,and heart meridians,and the flavored drugs of Xiao Chaihu Decoction mostly belong to the spleen,heart,and stomach meridians,the flavored drugs of Xuanfuhua Decoction mostly belong to the spleen,lung,and liver meridians,and the flavored drugs of the other classic prescriptions mostly belong to the spleen,stomach,and lung meridians.Conclusion:1.In the ancient books of traditional Chinese medicine,the prescription for treating coronary heart disease(chest pain and heartache)with the addition and subtraction of classics began to increase in the Song Dynasty and reached the peak in the Qing Dynasty.2.In the ancient books of traditional Chinese medicine,the treatment of coronary heart disease(chest pain and heartache)with the addition and subtraction of classic prescriptions is mainly to wenzhongbuxu and tongyangqutan,supplemented by qingrekuanxiong and qingxieshaoyang.The classic prescriptions with the effect of xinwentongyang are mostly selected.3.When using classic prescriptions to treat coronary heart disease(chest obstruction and heartache),ancient physicians often started from the pathogenesis of "yangweiyinxian",and attached importance to the compatibility of phlegm-resolving,cough-relieving and asthma-relieving drugs,qi-regulating drugs,interior-warming drugs,and exterior-relieving drugs.The drugs were mainly warm in nature,bitter in taste,warming yang qi,promoting qi circulation and removing stagnation,and at the same time paying attention to protecting the spleen and stomach.This may be because ancient cold were the main factor causing coronary heart disease,and in addition,it cannot be ruled out that some of the prescriptions for heartache are confused with a stomachache when they are included.