Characteristics Of Maternal Fever In Labor Analgesia With Wireless Continuous Temperature Monitoring And Effects On Maternal And Infant

Objective:we adopted wireless continuous temperature monitoring to collect data on maternal axillary temperature,demographic characteristics,delivery information,analgesia related information,maternal and infant complications throughout the peripartum period.Aims:Exploring the characteristics of febrile labor,analyzing the relationship between peripartum fever and anesthesia level,cervical dilation,analgesic doses and time duration,laying the foundation for exploring the mechanism of peripartum fever;studying the impact of peripartum fever on mother and infant,and providing the basis for rational clinical diagnosis and treatment.Methods:Parturient who received epidural analgesia during childbirth in Sichuan Provincial People’s Hospital and Jinjiang Maternal and Child Health Hospital from January 2021 to August 2021 were selected.During the labor,the body temperature ≥38℃ were included in the fever group,the body temperature<38℃ were included in the no-fever group.We collected and analyzed the following data:1.compared the relationship between the level of anesthesia,cervical dilatation,length of each labor,length of epidural analgesia and amount of analgesic drugs,and rate of turbid amniotic fluid(Ⅲ°)with fever in the perinatal period in the two groups;2.Compared the relationship between perinatal hemorrhage,antibiotic exposure rate,hospital days after delivery,neonatal Apgar score,rate of admission to NICU after delivery,length of neonatal NICU stay,and incidence of neonatal pneumonia with fever in the perinatal period in the two groups.Results:208 maternal cases were collected,and 166 cases were finally included in the analysis.The perinatal fever rate was 25.9%(43/166).There was no statistical difference in the baseline information between the two groups(P>0.05)Compared to the non-febrile group,the febrile group had a higher level of anesthesia(62.8%vs 35.3%;P=0.002),longer duration of first and total labor(P<0.5),higher rate of amniotic fluid turbidity(Ⅲ°)(18.6%vs 6.5%;P=0.033),longer duration of epidural analgesia(8.32(6.60,11.20)hour vs 6.25(4.5,10.50)hours;P=0.008),more analgesic medication(79(58,92)ml vs.56(37,92)ml;P=0.005),and higher usage of antibiotics(65.1%vs.45.5%;P=0.042).The probability of first fever after 8 cm of cervical dilatation was higher in febrile women(81.4%),and fever may occur not only during labor but also at the end of labor.No significant differences were seen between the two groups in maternal bleeding,length of stay after delivery,and neonates in 1 min Apgar score,5 min Apgar score,NICU admission after delivery,length of NICU stay,and incidence of neonatal pneumonia(P>0.05).Conclusions:1.Fever may occur not only during labor,but also after the end of labor.Compared with the non-febrile group,the febrile group had a higher level of anesthesia,longer duration of first and total labor and epidural analgesia,and more epidural analgesic drugs,and the women were more likely to have fever at cervical dilatation to 8 cm and beyond.2.On maternal and neonatal adverse events,maternal antibiotic exposure was greater in the febrile group compared with the non-febrile group,but there were no significant differences in other aspects.