| Research objective:In this study,the tongue image related parameters of patients with type 2 diabetes were collected by using Daosheng’s tongue surface diagnosis and pulse information collection system(DS01-B、DS01-D11),and their age,gender,complications,BMI,laboratory indicators and other information were collected to understand the general law of the progress of T2DM.The differences of syndrome types,symptoms and tongue features of T2DM with a course of less than 5 years,5 years ≤ course of disease ≤ 10 years and a course of disease > 10 years were preliminarily compared and analyzed,and the distribution characteristics of syndrome types,symptoms and tongue features of the three were discussed,in order to provide reference for TCM syndrome differentiation and treatment of T2DM with different course of disease.Research method:From November 2019 to February 2021,180 T2DM patients who met the inclusion and exclusion conditions were selected from the outpatient department of endocrinology of the Second Affiliated Hospital of Tianjin University of traditional Chinese medicine.They were recorded with a unified case form,including general data,medical history data,TCM syndrome data and laboratory indicators,The tongue diagnosis and pulse information collection system is used to collect and record the patient’s tongue information(data such as tongue quality,tongue shape,tongue color and fur color).SPSS is used to input data,set independent variables and dependent variables,select statistical analysis methods,sort out data,analyze data and draw conclusions.Research results:1.Among 180 patients with T2DM in this study,there were 81 males and 99 females,with a male to female ratio of 1:1.22.There was no significant difference between the two groups(P = 0.152);The average age of the group with disease course ≤ 5 years(marked as C1group)was(57.00 ± 9.88)years old,the group with disease course ≤ 5 years(marked as C2group)was(62.52 ± 8.09)years old,and the group with disease course > 10 years(marked as C3 group)was(61.73 ± 9.02)years old.There was no significant difference between the three groups.2.The analysis of the complications of the three groups showed that the frequency of DKD,CAHD and DPN increased with the increase of the course of disease.The difference among the three groups was statistically significant(P < 0.05),among which Dr had significant statistical difference(P < 0.01).The comparison between two groups showed that there were significant differences in C1 and C3 groups of DKD,CAHD,DPN and Dr(P<α’)。3.In the analysis of laboratory indexes of different course of disease,FGB,Hb Alc,HDL-C,LDL-C,TC,TG and other indexes have no statistical difference,HOMA-IR,U β The value of 2-mg increased with the increase of the course of disease,and the difference was statistically significant.4.The analysis results of TCM syndrome types of the three groups of patients show that the syndrome types with the most frequent frequency in the three groups are Qi Yin deficiency and deficiency syndrome.Compared among the three groups,yin deficiency,dryness and heat syndrome accounts for more in group C1(35.00%),and blood stasis and venation syndrome accounts for more in group C3(21.67%).5.The results of TCM symptom analysis of the three groups of patients show that the most frequent symptoms in each group are frequent urination at night.In addition,the two most frequent symptoms are dry throat and dry mouth,thirst and drinking in group C1,dry throat and dry mouth,palpitation and insomnia in group C2,and thirsty and drinking,spontaneous sweating and night sweating in group C3.The three groups were more frequent in the night,frequent urination,low waist and knees,sticky,sticky,tired,sweating,frequent urination,abdominal distention,congestion and voidity / foam frequency.The frequency of pharynx dryness increased with the increase of the course of disease,but the difference was not statistically significant(P>0.05).There was significant difference between the three groups(P < 0.05),and there was significant difference among the three groups(P = 0.004).There was significant difference between C1 group and C3 group(P< α’)。6.The frequency of red tongue increased by 6.6% in the three groups;In terms of moss color,the proportion of white moss was the most,and the proportion of white moss gradually increased and the proportion of yellow moss gradually decreased with the increase of disease course,the difference was statistically significant;In the comparison of tongue shape,the frequency of fat and thin tongue gradually increased with the increase of the course of disease,and the frequency of fat and thin tongue gradually decreased with moderate fat and thin.The difference was statistically significant(P < 0.05).There was significant difference among the three groups(P = 0.004).Research conclusion:1.The longer the course of T2DM,the more likely it is to be combined with DKD,CAHD,DPN and Dr,suggesting that the course of T2DM is one of the main risk factors.2.The longer the duration of T2DM and homa-2 β The value of 2-mg is more likely to be high,suggesting that IR and renal function damage in T2DM patients are closely related to the course of disease.3.Deficiency of Qi and Yin is the main syndrome type of T2DM.Deficiency of Yin,dryness and heat syndrome is more common in the early stage of the disease,and blood stasis and venation syndrome is more common in the late stage of the disease.4.With the increase of the course of disease,the proportion of light red tongue and yellow fur gradually decreased,and the proportion of dark red tongue and white fur gradually increased,suggesting that the heat image of T2DM patients gradually decreased and blood stasis gradually aggravated with the progress of the course of disease. |
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