Meta Analysis Of The Efficacy Of Acupuncture Combined With Point Injection In The Treatment Of Sciatica

Objective:With evidence-based medicine’s principles and methods,as well as using Meta analysis,evaluating the efficacy of acupuncture combined with point injection,objectively,in the treatment of sciatica.Besides,comparing it with the efficacy of acupuncture alone and with point injection alone in the treatment of sciatica.Finally,obj ective evidence-based medical evidence will be provided for sciatica’s clinical treatment.Method:Making a literature search strategy,conducting searches in 8 databases from January 1,2011 to December 3 1,2021.After deduplicating,preliminary screening,re-screening,extracting data information,according to the present inclusion and exclusion criteria.Risk of bias analysis,Meta-analysis and quality of evidence grade were performed on the included literature by using the risk of bias assessment tool provided by the Cochrane Collaboration,Review Manager 5.3 software and GRADEpro software.Results:1 Results of literature review Finally,25 Chinese literatures were included in this study.There were a total of 2424 patients,including 1289/852 males/females,and 1231/1193 patients in the observation group/control group.In the light of the differences of control measures,the patients were divided into 2 groups:acupuncture+acupoint injection VS acupuncture;acupuncture+acupoint injection VS acupoint inj ection.2 Risk of bias analysis Selection bias:9 articles were low risk,12 articles were unknown risk,and 4 articles were high risk;3 articles were low risk,and 22 articles were unknown risk.The average risk of implementation bias was unknown in 25 articles.The average risk of measurement bias in 25 articles was unknown.Follow-up bias:4 were high risk and 21 were low risk.Publication bias:3 high risk,22 low risk.All 25 articles of other biases were at low risk.3 Results of Meta-analysis3.1 Effective rate Acupuncture+Point injection VS Acupuncture:RR=1.18,95%CI[1.13,1.22];Acupuncture+Point injection VS Point injection:RR=1.26,95%CI[1.17,1.36]。3.2 Cure rate Acupuncture+Point injection VS Acupuncture:RR=1.61,95%CI[1.42,1.81];Acupuncture+Point injection VS Point injection:RR=1.53,95%CI[1.10,2.13]。3.3 Visual analogue score Acupuncture+Point injection VS Acupuncture:MD=-0.95,95%CI[-1.3 5,-0.5 5];Acupuncture+Point injection VS Point injection:MD=-1.24,95%CI[-1.75,-0.73]。4 Quality of evidence The GRADEpro software was used to grade the 6 outcome indicators’ quality of evidence for the intervention measures:acupuncture+point injection VS acupuncture,acupuncture+point injection VS point injection,the total effective rate,cure rate and visual analog score.Finally,advanced VS intermediate VS Low VS Very Low=0 VS 3 VS 1 VS 2.Overall quality is low.Conclusion:1.In the treatment of sciatica,acupuncture combined with point injection,compared with simple acupuncture and simple point inj ecti on,can improve the total effective rate and cure rate of treatment and reduce pain.2.When treating sciatica,in terms of total effective rate,acupuncture combined with point injection is better than acupuncture than point injection;in terms of cure rate:acupuncture combined with point inj ecti on is better than point injection than acupuncture.3.Acupuncture combined with point inj ecti on in the treatment of sciatica has fewer adverse reactions,lower recurrence rate and has advantages in clinical using.