A Network Meta Analysis Of Insomnia Treated By Common External Therapies Of Traditional Chinese Medicine

Objective:This research used the method of network meta-analysis to compare the therapeutic effect of common external treatment methods of Traditional Chinese Medicine in treating insomnia.Then according to the efficacy of the intervention measures,to provide new ideas and evidences for the treatment of insomnia.Methods:The research used the method of network meta-analysis.The literature retrieval includes electronic and manual retrieval.CNKI,Wanfang,VIP,PubMed and The Cochrane Library databases were searched by computer.According to Cochrane Handbook 5.1.0,the methodological quality of included literature was evaluated.Stata network software was used for frequency analysis.Results:1.51 RCTs were included.A total of 4338 patients with insomnia were included.It contains five external treatments of Traditional Chinese Medicine to treat insomnia,which are acupuncture,moxibusti on,auricular point sticking,acupoint sticking,massage.2.A total of 39 studies reported the treatment effect of insomnia,involving 6 interventions.The SUCRA ranked as follows:acupuncture+auricular point sticking(93.4%)>massage(78.9%)>acupuncture(49.9%)>acupoint sticking(48.3%)>acupuncture+moxibustion(22.8%)>routine(22.8%).3.A total of 32 studies reported the effect of PSQI declining,involving 8 interventions.The SUCRA ranked as follows:acupuncture+auricular point sticking(95.4%)>acupuncture(69.8%)>massage(65.5%)>auricular point sticking(48.5%)>moxibustion(3 8.4%)>acupuncture+moxibusti on(34.3%)>acupoint sticking(28.2%)>routine(19.8%).4.Its 51 articles are random,there are 31 articles specify the random method。Five articles described the cases and the reasons of the lost to follow-up,fall off,the other literature did not mention.This study mainly bias from the double blind test method,Statistical results,the high risk of bias literature quantity within 1 0%.Conclusion:1.External treatment of Traditional Chinese medicine can effectively treat insomnia and reduce the pressure of Pittsburgh sleep quality index(PSQI).Acupuncture can effectively reduce the self-evaluation of insomnia patients with anxiety scale(SAS),depression self rating scale(SDS),Athens insomnia scale(AIS)score,and Increase 5-hydroxytryptamine(5-HT)content.Acupuncture treatment had no significant effect on Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD)scores.2.Acupuncture combined auricular application has more advantages in treating insomnia and reducing PSQI.