Objective:Through data mining,analyze the prescriptions for the treatment of menstrual volume after IUD placement,summarize the law of clinical traditional Chinese medicine,and explore the clinical efficacy of duanhong point combined with anchong Decoction in the treatment of menstrual volume after IUD placement,in order to provide a strong basis and reasonable treatment scheme for the clinical application of traditional Chinese medicine in the diagnosis and treatment of this disease.Methods:1.Retrospective study: by searching the literature related to the treatment of traditional Chinese medicine with large menstrual volume after birth control ring placement in Chinese traditional medicine database,Chinese basic knowledge database,Chinese biomedical literature database,VIP database and Wanfang database,the use frequency and action category of traditional Chinese medicine were analyzed by descriptive statistics,and the association rules of traditional Chinese medicine were analyzed by IBM SPSS modeler 18.0software.2.Clinical study: 33 patients who met the diagnostic inclusion criteria of traditional Chinese and Western medicine were enrolled in this study.A total of 2 patients fell out during the study period,and 31 patients were actually completed.The patients were treated with acupuncture and moxibustion at duanhong point combined with the modified anchong Decoction for 3 consecutive menstrual cycles.By calculating the score and total score of primary and secondary syndromes of traditional Chinese medicine,PBAC score and MS-QOL score,the statistical software spss26.0 for data processing and analysis.Results:1.Retrospective study:(1)Analysis of frequency of use of traditional Chinese medicine: 141 traditional Chinese medicines were involved in the study,with a total frequency of 1727 times,of which the cumulative frequency of use of 30 traditional Chinese medicines was 1253 times,with a cumulative frequency of 72.55%.The top five high-frequency traditional Chinese medicines were Rehmannia glutinosa,Angelica sinensis,Astragalus membranaceus,Puhuang,and Rubia.(2)Analysis on the use categories of traditional Chinese medicine: a total of 18 categories of traditional Chinese medicine are involved,including hemostatic drugs,heat clearing drugs,Qi tonifying drugs,blood tonifying drugs and blood activating drugs,ranking the top 5,with a total frequency of 1312 times and a frequency of 75.97%.(3)Analysis of drug association rules: a total of 21 association rules with support greater than 0.1 and confidence greater than 0.8 were generated,of which 4 association rules had confidence of 1.In association rules,dandelion,wulingzhi,Angelica sinensis,Astragalus membranaceus,Codonopsis pilosula,Rehmannia glutinosa,Rubia and white peony are in the center of association.The associations with a high degree of association and a confidence greater than 0.9 include {wulingzhi} = > {Puhuang},{wulingzhi,motherwort} = >{Puhuang},{wulingzhi,Rubia} = > {Puhuang},{Angelica sinensis} = > {Atractylodes macrocephala,Codonopsis pilosula} = > {Astragalus},{Chuanxiong} = > {Angelica sinensis},{Ligustrum}.2.Clinical research(1)PBAC score: Before treatment,compared with the first menstrual cycle,the second menstrual cycle and the third menstrual cycle,PBAC scores decreased significantly(P <0.01);There was no significant difference in PBAC score between the third menstrual cycle and follow-up period(P > 0.05).(2)MS-QOL scale score: the degree and time scores of activity limitation,fatigue limitation,irritability and depression were significantly improved before and after treatment(P < 0.01).(3)TCM syndrome score: Compared with the first menstrual cycle,the second menstrual cycle and the third menstrual cycle before treatment,the total score of traditional Chinese medicine syndrome decreased significantly(P < 0.01);There was significant difference in the total score of TCM syndrome between the third menstrual cycle and the follow-up period(P < 0.05).The scores of primary and secondary syndromes of traditional Chinese medicine decreased before and after treatment,and the difference was statistically significant(P < 0.05).(4)Analysis of curative effect after treatment: after three complete menstrual cycles,the total effective rate of TCM syndrome was 96.77%,and the total clinical effective rate was93.55%.Conclusion:1.In the traditional Chinese medicine treatment of menorrhagia after birth control ring placement,the top five drugs with the highest frequency are Rehmannia glutinosa,Angelica sinensis,Astragalus membranaceus,Puhuang,and Rubia;In the category of traditional Chinese medicine,hemostatic drugs,heat clearing drugs,Qi tonifying drugs,blood tonifying drugs and blood activating drugs rank in the top five;In the association rules,Puhuang,wulingzhi,angelica,astragalus,Codonopsis pilosula,Rehmannia glutinosa,Rubia,Radix Paeoniae Alba,etc.are at the center of the association,with a high degree of association.2.Duanhong acupoint combined with anchong Decoction in the treatment of menorrhagia after IUD placement can effectively reduce the amount of menstruation,improve relevant TCM syndromes and improve the quality of life of patients.It plays a significant role in clinical efficacy and long-term efficacy,and there is no adverse reaction in the treatment process,so it is suitable for clinical practice. |