| Objective:To collect the basic data of patients with non-syndromic cleft lip with palate who treated in Baise from 2013 to 2021,and to understand the pathogenesis characteristics of patients with cleft lip and palate in Baise.At the same time,various factors affecting the occurrence of palatal fistula in patients with non-syndromic cleft palate were collected and analyzed.To provide a theoretical basis for preventing the occurrence of palatal fistula after non-syndromic cleft palate surgery and reduce the incidence of palatal fistula after clinical cleft palate surgery.Methods:By collecting the information of non-syndromic cleft lip with palate patients who treated in Baise from 2013 to 2021,the collected patient information was entered into the EXCEL form,and statistical analysis of the composition ratio of relevant information.At the same time,the basic information of non-syndromic cleft palate patients who have completed cleft palate repair surgery was collected by reviewing historical medical records and telephone return visits.According to the related research on non-syndromic cleft palate at home and abroad,the factors that may affect the occurrence of palatal fistula were screened out.Univariate analysis was performed on the screened suspicious influencing factors by Chi-square test,and then a collinearity diagnostic analysis was performed on the meaningful influencing factors.Excluding the influencing factors with high similarity,binary logistic regression analysis was used to compare the influence of various factors on the occurrence of palatal fistula after cleft palate surgery.Results:(1)This study showed that there were 423 patients with cleft lip with palate who were treated in Baise from 2013 to 2021,including 92 cases of simple cleft lip,128 cases of simple cleft palate,and 203 cases of cleft lip combined with cleft palate.(2)According to gender statistics,there were 246 male patients and 177 female patients,male:female=1.4:1.(3)Statistics from different ethnic groups show that the Zhuang nationality has the largest number of patients with 199 cases,followed by the Han nationality with 152cases;Yao nationality with 28 cases,Miao nationality with 22 cases,and Yi nationality with22 cases.(4)According to statistics from different regions,Youjiang District has the most patients with cleft lip and palate,while Lingyun County and Pingguo City had the fewest patients born;190 of them are from urban areas,and 233 are from rural areas.The patients with cleft lip and palate from rural areas are 1.2 times in urban areas.(5)The Chi-square test was used to analyze the influencing factors of palatal fistula in patients with non-syndromic cleft palate in Baise.There were statistically significant differences in the influence of factors such as whether to undergo reoperation,whether to receive continuous nursing care,etc.on the occurrence of postoperative palatal fistula(P<0.05).The difference was not statistically significant(P>0.05).(6)Binary Logistic regression analysis showed that the palatal soft tissue fissure width,re-cleft palate repair,dietary habits and whether receiving continuous nursing had significant effects on the occurrence of postoperative palatal fistula(P<0.05).Conclusion:(1)Among the patients with cleft lip and palate treated in Baise,the number of patients with cleft lip and cleft palate was the largest,and the number of patients with simple cleft lip was the least.(2)Among the patients with cleft lip and palate in Baise,the number of male patients is more than that of female patients.(3)Among the cleft lip and palate patients included in this study,the Zhuang nationality had the largest number of cleft lip and palate patients,followed by the Han nationality,and the least number of other ethnic minorities.(4)Among the patients with cleft lip and palate treated in Baise,Youjiang District had the most patients with cleft lip and palate,and the least patients were born in Lingyun County and Pingguo City;more patients were from rural areas than urban patients.(5)This study found that the palatal soft tissue fissure width≥16 mm was an independent risk factor for the occurrence of palatal fistula,and patients with palatal soft tissue fissure width≥16 mm had a higher risk of postoperative palatal fistula.(6)This study found that repeated cleft palate repair was an independent risk factor for the occurrence of palate fistula.Patients who underwent cleft palate repair again had a higher risk of postoperative palate fistula than those who underwent cleft palate repair for the first time.(7)This study found that continuous nursing is an influencing factor for the occurrence of palatal fistula.Patients who did not receive continuous nursing were more likely to develop palatal fistula after cleft palate repair.(8)This study found that patients with rice flour as the main food 2 weeks after surgery had a higher risk of developing palatal fistula after cleft palate repair. |
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