Study On The Effect Of Different Calorie Supply On The Prognosis Of Patients With Septic Shock

Objective:To compare the effects of different calorie supply on the prognosis of patients with septic shock in order to provide the best calorie supply for patients with septic shock.Methods:Using the method of retrospective analysis,the clinical data of 100 patients with septic shock who met the inclusion criteria from August 2019 to August 2021 were selected and divided into group A and group B according to non-protein calorie supply.The feeding method of group A was progressive feeding.The calorie reached 70% of the target calorie on the third day of ICU,and gradually increased the calorie to reach the target calorie on the 7th day.The feeding method of group B was isocaloricdiet,and70%-100% target calorie feeding was from day 1 to day 7.The general data of the two groups were similar at admission,and the amount of protein provided was similar.The daily calorie supply,protein supply,nutritional index,liver and kidney function,blood glucose,insulin dosage,mechanical ventilation time,hospitalization time,ICU stay time,hospital infection rate,ICU mortality and 28-day mortality were collected and compared between the two groups.To explore the relationship between calorie supply and prognosis of patients with septic shock.Results:There were no statistically significant differences in nutritional indicators,liver and kidney function and blood glucose between the two groups in nutritional support D7(P >0.05).The amount of insulin in group A was less than that in group B,and the difference was statistically significant(P < 0.05).Compared with group B,mechanical ventilation time,hospital stay and ICU stay in group A were shorter than those in group B,and the differences were statistically significant(P < 0.05).Compared with group B,the nosocomial infection rate and 28-day mortality in group A were lower than those in group B,and the differences were statistically significant(P < 0.05),while the difference in ICU mortality was not statistically significant(P > 0.05).Conclusion:When providing sufficient protein,patients with septic shock were given hypocaloricorunder-feeding in the early acute stage(1-3 days)and isocaloricdiet in the acute late stage(4-7 days).It can reduce the demand for insulin,shorten the time of mechanical ventilation,hospital stay and ICU,reduce the nosocomial infection rate and28-day mortality to improve the prognosis.In fact,different periods of organ function damage in septic shock will have different results,so the individual treatment of severe patients is the most appropriate.