Effect Of Continuous Pump Infusion Of Remifentanil During Periextubation On The Diameter Of Optic Nerve Sheath During Tracheal Extubation In Patients Undergoing Meningioma Resection

Objective:Measurement of optic nerve sheath diameter by bedside ultrasound effect of continuous infusion of remifentanil during extubation on optic nerve sheath diameter during tracheal extubation in patients with meningioma.Methods:Sixty patients who underwent craniofrontal meningioma resection in supine position under general anesthesia were randomly divided into remifentanil group(Group R)and normal saline group(Group C).Both groups were given total intravenous anesthesia.The types of anesthesia induction and maintenance drugs used in each group were the same.After induction,endotracheal intubation and mechanical ventilation were performed.The optic nerve sheath diameter(ONSD)and basic vital signs were recorded at the end of operation(T0),immediately after extubation(T1),3min(T2),5min(T3)and 10min(T4);The awakening time,extubation time and the degree of extubation choking were compared,and the adverse reactions such as nausea,vomiting and respiratory depression were observed.Results:Compared with T0,bilateral ONSD in T1 ～ T3 groups was widened(P < 0.05);Compared with group C,the ONSD of Group R decreased significantly from T1 to T3(P< 0.05);The degree of choking cough in group C was significantly higher than that in Group R(P < 0.05);There was no significant difference in postoperative wake-up time,extubation time,nausea,vomiting and respiratory depression between the two groups.Conclusion:Continuous pump injection of rifentanil during periextubation can reduce the increase of optic nerve sheath diameter during tracheal extubation in patients undergoing meningioma resection to a certain extent.