| Objective Through the evaluation of TCM syndrome score scale,ASAS20 curative effect evaluation scale,CRP,ASDAS-CRP activity evaluation scale,BASMI measurement index scale and related data analysis,to explore the effects and clinical effects of wheat moxibustion and oral celecoxib on patients with ankylosing spondylitis(kidney deficiency and cold type).MethodsIn this study,76 patients with ankylosing spondylitis(kidney deficiency and cold type)were randomly divided into control group(38 cases)and observation group(38 cases).The control group was treated with celecoxib capsule once a day,200 mg once a day,and the observation group was treated with wheat grain moxibustion twice a week from Monday to Friday,with an interval of at least 3 days),the first moxibustion group(Baihui,Dazhui,Zhiyang,Yaoyangguan)and the second moxibustion group(Zhongwan,Guanyuan).Both groups were treated continuously for 12 weeks,every 6 weeks as a course of treatment,a total of 2 courses of treatment.Before and after treatment,the patients in the above two groups were evaluated by TCM syndrome score scale,ASAS20 curative effect evaluation scale,CRP,ASDAS-CRP activity evaluation scale and BASMI measurement index scale,and the data were analyzed by SPSS25.0 software.Results1.Baseline comparison: Finally,69 cases were included,including 35 cases in the control group and 34 cases in the observation group.The baseline of the two groups before treatment was the same and comparable.2.Laboratory observation index: The CRP of the observation group after treatment was significantly lower than that of the control group(P<0.01).3.Result of the treatment:(1)Comparison of TCM clinical syndrome scores: The total score of the observation group after treatment was significantly lower than that of the control group after treatment(P<0.01).After treatment,the overall effective rate of the control group was 62.85%,and that of the observation group was 94.11%.The curative effect of the observation group after treatment was significantly better than that of the control group(P<0.01).(2)Comparison of ASAS20 scores: The total score of the observation group after treatment was significantly lower than that of the control group after treatment(P<0.01).The overall ASAS20 standard rate of the control group after treatment was 62.85%,and the overall ASAS20 standard rate of the observation group after treatment was 85.29%.The curative effect of the observation group after treatment was better than that of the control group after treatment(P<0.05).(3)Comparison of ASDAS-CRP score: The total ASDAS-CRP score of the observation group was significantly lower than that of the control group(P <0.01).(4)Comparison of BASMI score: The total score of the observation group after treatment was significantly lower than that of the control group(P<0.01).Conclusions1.The wheat grain moxibustion therapy under the guidance of the academic thought of "Tong Tiao du Ren" can not only effectively reduce the level of CRP inflammation,but also improve the clinical symptoms of patients with ankylosing spondylitis of kidney deficiency and cold type,and the overall curative effect is better than that of celecoxib capsule,especially in the five aspects of lumbosacral back pain,morning stiffness,fear of cold,lukewarm hands and feet,and sore waist and knees.The efficacy of oral celecoxib capsule is similar to that of oral celecoxib capsule in nocturnal pain,cold scrotum(male)or leucorrhea(female)and peripheral swelling pain.2.Wheat grain moxibustion can improve the motor dysfunction and improve the quality of life of the patients.the therapeutic effect of wheat grain moxibustion is better than that of oral celecoxib capsule in the score of motor function and the objective index of measurement,especially in the activities of lumbar vertebrae and cervical vertebrae. |