| Objective: Based on the traditional concept of "treating Shen" and "timing" intervention of acupuncture,this paper uses modern electroophthalmic collection and analysis technology and biofeedback technology to capture the electroophthalmic signals in the real-time attention state of the children,so as to guide the trigger timing of percutaneous electrical stimulation at Changqiang acupoint.To explore the clinical efficacy of transcutaneous electrical acupoint stimulation(TEAS)based on electro-optic biofeedback technology combined with rehabilitation therapy in children with intellectual disability.Methods: Sixty children with intellectual disability who met the inclusion criteria were randomly divided into control group and treatment group,with 30 cases in each group.The control group was treated with conventional rehabilitation,while the treatment group was treated with TEAS of Changqiang acupoint based on electro-optic biofeedback technology.The researchers fixes the instrument device on the posterior lumbar side of the subjects by posted magic belt.The input electrodes are attached to the eye of the children,and the output electrodes are attached to the Changqiang acupoint of the children.Before treatment,collect the meaningful Electro-oculogram(EOG)signals of each children and set the trigger threshold of themselves.The acquisition process of EOG signals is synchronized with daily life and training.When the EOG signals of the treatment group reaches the trigger threshold,20 s of percutaneous electrical stimulation of Changqiang acupoint will be immediately generated.At the same time,researchers recorded the trigger period and number of times.It lasts 30 min each time,twice a week.One course of treatment is totally 4 weeks,and there are three courses at all.At the end of each course,the S-M and Goal Attainment Scaling(GAS)are used as the main efficacy indicators for evaluation.After noise reduction,the EOG signals are calculated by using nonlinear dynamics analysis methods such as approximate entropy and correlation dimension,and the results are used as observation indicators together with the EOG threshold to explore the correlation between EOG signals and the cognitive level of children with ID,and to evaluate the efficacy in different states.Results: 1.Efficacy evaluation:(1)Compared with those before treatment,the scores of GAS in the treatment group after the first,second and third courses of treatment are all significantly different(P<0.001).Compared with those after the first course,the scores of GAS in the treatment group after the second and third courses of treatment are also significantly different(P<0.05,P<0.01).However,there is no significant difference in the scores of S-M in the treatment group before and after each course of treatment(P> 0.05).Compared with those before treatment,the scores of GAS in the control group after the first,second and third courses of treatment are all significantly different(P<0.001).Compared with those after the first course,the scores of GAS in the control group after the second and third courses of treatment is also significantly different(P<0.05,P<0.01).(2)Intention to treat analysis: The scores of social activity,large motor ability and GAS scales in the treatment group after three courses of treatment are significantly different from those in the control group(P<0.05).The scores of self living ability and GAS in the treatment group after three courses of treatment are significantly different from those before treatment(P<0.01,P<0.001).The scores of communication ability and GAS in the control group after three courses of treatment were significantly different from those before treatment(P<0.05,P<0.001).2.EOG signal analysis based on nonlinear dynamics:(1)Efficacy analysis under different states: After treatment,the total EOG approximate entropy(Ap En)of the guided and active states are significantly different from that before treatment(P≤0.001,P< 0.01).And the average EOG Ap En of the guided and active states are also significantly different from that before treatment.Before and after treatment(P<0.05).However,there is no significant difference in the correlation dimension of each state(P> 0.05).(2)Correlation analysis with cognitive level : under the two groups of combined cases,the average EOG threshold of baseline is negatively correlated with communication ability and S-M standard score(P<0.05,r=-0.312,r=-0.307).The maximum EOG threshold of baseline is negatively correlated with communication ability and S-M standard score(P<0.05,r=-0.318,r=-0.310).The average EOG Ap En of the third course of treatment is negatively correlated with the GAS(P<0.05,r=-0.460).The average EOG threshold of the baseline in the treatment group is negatively correlated with communication,occupation and self living ability(P<0.05,r=-0.363,r=-0.373,r=-0.389).It shows a low negative correlation between the baseline maximum EOG threshold of the treatment group and communication ability(P<0.05,r=-0.363).The baseline correlation dimension of the treatment group is negatively correlated with the ability of participate in social activity,communication,occupation and self living(P<0.05,r=-0.388,r=-0.433,r=-0.409).Conclusions: 1.TEAS combined with rehabilitation therapy based on electro-optic biofeedback technology has good clinical curative effect on children with intellectual disability.It is superior to the control group in terms of self living,social activity and large motor ability,which is worthy of clinical application and promotion.Compared with the S-M,the GAS can better reflect the individual progress of children with intellectual disability.2.The average EOG threshold can reflect the communication,occupation and self living ability of children,and the maximum EOG threshold can reflect the communication ability of children.Total EOG Ap En and average EOG Ap En can reflect the changes of children before and after treatment under guided and activity.The correlation dimension can reflect the children’ s ability to social activity,communication,occupation and self living. |
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