Correlation Analysis Of Vestibular Function And Electrocochleography With The Prognosis Of Sudden Sensorineural Hearing Loss

Objective:To analyze the results and characteristics of vestibular function and electrocochleography in patients with unilateral sudden sensorineural hearing loss(SSNHL).To analyze the results and characteristics of vestibular function and electrocochleography in patients with unilateral SSNHL,combined with the basic data and audiological examination of patients,to explore the prognostic factors affecting of SSNHL.Provide directions for the examination and treatment of patients with SSNHL.Methods: 1.A total of 165 patients with unilateral SSNHL who were treated in the Department of Otology,Yan’an University Affiliated Hospital from October 2019 to December 2021 were selected.According to the inclusion and exclusion criteria,134 patients were finally selected.2.All included patients underwent pure tone audiometry,caloric test(CT),vestibular evoked myogenic potential(VEMP),video head impulse test(v HIT)and electrocochleography(ECoch G),and record the examination results.The patients were treated for 14 days in accordance with the Chinese Medical Association Guidelines for the Diagnosis and Treatment of SSNHL(2015),the pure tone audiometry was performed at the end of the treatment,and the efficacy was graded according to the audiometry results before and after treatment.3.Statistical analysis was performed using SPSS 25.0.Factors that may affect the prognosis of SSNHL,such as gender,age,side of the affected ear,days of onset,accompanying symptoms,diabetes,hypertension,degree of hearing loss,type of hearing curve decline,CT results,VEMP extraction rate,bilateral amplitude ratio,asymmetry,P1,N1 latency,P1-N1 amplitude,gain value of each semicircular canal on the affected side of v HIT,ECoch G elicitation and SP/AP ratio and efficacy were subjected to univariate analysis,and P<0.05 was included in multivariate logistics Regression analysis,P<0.05 was considered statistically significant.Results:1.Univariate analysis showed that gender,side of affected ear,age,tinnitus,ear fullness,diabetes,hypertension were not significantly correlated with prognosis(P>0.05).There were statistically significant differences in the presence or absence of dizziness,days of onset,degree of hearing loss,type of hearing loss and curative effect(P<0.05).2.There were statistically significant differences in CT results between the normal group and the abnormal group,the v HIT gain value between the normal group and the abnormal group,and the ECoch G elicitation and non-eliciting and the prognosis of SSNHL(P<0.05).There were significant differences in v HIT level,anterior and posterior semicircular gain values between the effective and ineffective groups(P<0.05).The SP/AP ratio in the ECoch G extraction group was significantly different between the effective group and the ineffective group(P<0.05).There was no significant difference in the elicitation rate of o VEMP and c VEMP,bilateral amplitude ratio,asymmetry,P1,N1 latency,and P1-N1 amplitude between the effective and ineffective groups of SSNHL(P>0.05).3.Multivariate logistic analysis showed that ECoch G,v HIT results and the degree of hearing loss had no significant effect on the prognosis of SSNHL(P>0.05).Accompanied by vertigo,onset days ≥ 7,abnormal CT results,and the type of hearing curve are the unfavorable factors affecting the prognosis of SSNHL.Conclusions:1.SSNHL patients with onset days ≥ 7 days,with vertigo,and abnormal CT results have poor prognosis.Hearing curve decline type has the worst prognosis in high-frequency decline type,followed by total deafness type and flat type,and low-frequency decline type has the best prognosis.2.CT combined with v HIT can comprehensively evaluate the semicircular canal function of SSNHL and provide guidance for the prognosis of SSNHL patients.3.It is still believed that the parameters of ECoch G and VEMP cannot evaluate the prognosis of SSNHL.