Objective:To investigate the clinical efficacy and safety of wrist-ankle acupuncture in patients with renal colic.To compare and analyze the difference between wrist-ankle acupuncture in the treatment of renal colic and intramuscular injection of non-steroidal anti-inflammatory drugs(ketorolac tromethamine 30mg)in the treatment of renal colic,providing a simple and effective treatment for renal colic,and promoting the clinical application of carpal and ankle needles.Methods: Using the clinical randomized controlled trial research method,the patients with renal colic who were admitted to the Department of Urology,Guangdong Provincial Hospital of Traditional Chinese Medicine from August 2019 to April 2020 and met the inclusion criteria were randomly divided into wrist and ankle according to the preestablished randomization plan.Acupuncture group(n1=60)and control group(n2=60).In the wrist-ankle acupuncture group,the patients with renal colic were treated according to the operation standard of wrist-ankle acupuncture therapy.All patients in the group were given pethidine hydrochloride for pain relief.Through differential analysis and comparison,the waiting time of patients for treatment was discussed;the therapeutic effect in different time periods,the overall curative effect,the24-hour pain recurrence rate and other efficacy indicators;the safety indicators such as adverse reactions and the addition of analgesic drugs were compared and analyzed between the two groups.The statistical method is to establish a database with Excel,use the statistical software SPSS 18.0 for data analysis,and the general data of patients is based on rank and test,χ~2-test and other methods.The waiting time for treatment was tested by t-test,and the VAS score at multiple time points was measured by repeated measurement of ANOVA,overall efficacy,24-hour pain recurrence,adverse reactions,and supplemental analgesic use ? 2-test.Result:Analysis of the general data of the two groups of patients showed that there was no significant difference in gender,age,body mass index(BMI),educational level,and comorbid diseases(P>0.05).The general data of the two groups of patients were comparable.1.Comparison of waiting time for treatment,the waiting time for wristankle acupuncture treatment was 1.18±0.45 min,and the waiting time for intramuscular injection drug treatment was 5.17±3.89 min.After statistical analysis,the difference was statistically significant(t=7.89,P<0.001).2.Comparison of pain VAS scores before and after treatment,repeated measures analysis of variance was used for the VAS scores of multiple observation time points in the two groups,and the differences in covariance matrix and spherical test were statistically significant(P<0.01),so the correction model(G-G model was used)GreenhouseGeisser),in the time test,F time = 1016.626,P = 0.000,indicating that the difference in data at each time point is statistically significant;the interaction effect(F time * group = 105.126,P = 0.001)is statistically significant,It shows that there is an interaction between time and grouping,and the treatment effect of each time period varies with different groups.The variance analysis was performed between the groups,and the difference between the groups was statistically significant(F between groups = 342.566,P< 0.001),indicating that the time factor will vary with the different groups,suggesting that the therapeutic effect of the wrist-ankle acupuncture group is better than that of the control group.3.In the overall efficacy evaluation,the total effective rate of the wristankle acupuncture group was 98.33%,while the total effective rate of the control group was 93.33%.There was no significant difference in the total effective rate between the two groups(P=0.19).4.There was no significant difference in the 24-hour pain recurrence rate between wrist-ankle acupuncture and intramuscular injection of ketorolac tromethamine 30 mg(χ~2=1.56,P=0.21).5.Compared with the occurrence of adverse reactions,wrist-ankle acupuncture treatment had fewer adverse reactions,and the difference was statistically significant(χ~2=5.92,P=0.02).6.There was no significant difference in the proportion of patients receiving additional analgesics,wrist-ankle acupuncture treatment and drug treatment(χ~2=0.70,P=0.68).Conclusion:1.Compared with intramuscular injection of non-steroidal antiinflammatory drug ketorolac tromethamine in the treatment of renal colic with wrist-ankle acupuncture,patients have a shorter waiting time for treatment.2.Compared with intramuscular injection of non-steroidal antiinflammatory drug ketorolac tromethamine in the treatment of renal colic,there is no statistically significant difference in the overall efficacy of wrist-ankle acupuncture,but wrist-ankle acupuncture can quickly take effect and relieve renal colic quickly.pain.3.Wrist-ankle acupuncture has better safety in the treatment of renal colic.Compared with intramuscular injection of non-steroidal antiinflammatory drug ketorolac tromethamine,it has fewer adverse reactions and higher safety. |