SEEK^flex Guiding Endotracheal Intubation To Reduce Stress Response And Airway Complications In General Anesthesia Patients

Objective:To observe the effects of SEEK^flex guided endotracheal intubation on stress response and postoperative airway complications of patients under general anesthesia,exploring its clinical application value.Methods:A total of 160 patients undergoing general anesthesia for elective surgery were randomly divided into two groups according to different intubation ways:the experimental group was the SEEK^flex-guided intubation group（80 patients）,and the control group was the conventional intubation group（80 patients）.In the experimental group,SEEK^flex was inserted into the glottis first,and then guiding the endotracheal tube through the vocal cords to the desired depth.In the control group,intubation was performed after the endotracheal tube with stylet was shaped at a certain Angle,and video laryngoscope was used in both groups.Before induction（T0）、before intubation（T1）,immediately after intubation（T2）,30s after intubation（T3）,1min after intubation（T4）,90s after intubation（T5）,2min after intubation（T6）,150s after intubation（T7）,3min after intubation（T8）,The HR,SBP,DBP and MAP of 2 groups were observed and recorded.Record the success of the first intubation、the intubation time.The complications such as sore throat,tooth injury and hoarseness were also recorded.Results:The fluctuation trend during intubation of HR,SBP,DBP and MAP was statistically different between the two groups（P<0.05）.The fluctuation of hemodynamic response in experimental group was obviously weaker than that in control group.MAP between the two groups differed from immediately after intubation（T2）to 90s after intubation,with statistical significance（P<0.05）.HR was mainly different from 30s（T3）to 90s（T5）after intubation,considered statistically significant（P<0.05）.SBP in the control group was higher than that in the SEEK^flex group immediately after intubation（T2）to 2min after intubation（T6）,and the difference was statistically significant（P<0.05）.There was a significant difference in DBP between the two groups from immediately after intubation（T2）to 1 minute after intubation（T4）（P<0.05）.During intubation,the maximum heart rate（HRmax）,maximum systolic blood pressure（SBPmax）,maximum diastolic blood pressure（DBPmax）,maximum mean arterial pressure（MAPmax）,and the differences of 4 hemodynamic indexes （ΔHR,ΔSBP,ΔDBP,ΔMAP）in the SEEK^flex group were all smaller than those in the control group（P<0.05）.In this study,the success rate of first intubation was 98.7%and 88.8%,respectively.The success rate of first intubation in experimental group was significantly higher than that in control group,with statistical significance（P=0.018）.The number of adjustments in SEEK^flex group was less than that in stylet group,with significant statistical difference（P=0.010）.The median intubation time in both groups was 18.0s,but the total intubation time in the experimental group was longer than that in the control group（P=0.008）.The incidence of hoarseness in the control group was significantly higher than that in the guide group,with statistical difference（P<0.001）.Conclusion:Using SEEK^flexto guide endotracheal intubation reduces intubation irritation,hemodynamic response after intubation,and postoperative complication rates while ensuring a high success rate.