The Distribution Of Tcm Syndromes Of Hfref And Hfpef Patients And Correlation Stuty

Objective:To observe the distribution characteristics of TCM syndromes in HFrEF and HFpEF,to explore the correlation between TCM syndromes and 6MWT and myocardial energy metabolism.Thus,it provides objective basis for TCM syndrome differentiation of HFrEF patients and HFpEF patients.Methods:A total of 240 patients who met the inclusion criteria were recruited from the cardiovascular department of the first affiliated hospital of Heilongjiang university of traditional Chinese medicine from September 2015 to February 2018.by collecting basic information of patients(name,gender,age),Vital signs(blood pressure,heart rate),Clinical manifestations(symptoms,signs,tongue veins),and the patients were divided into three groups:Qi deficiency blood stasis group,Qi Yin deficiency blood stasis group,Yang Qi deficiency and blood stasis group.6MWT and Cardiac ultrasound examination were performed in each group,to observe the differences between different syndromes of two types of patients in 6MWT,MEE and other indicators.Logistic analysis of various TCM syndromes and corresponding indexes,and the correlation analysis of Pearson among various indicators,and use SPSS22.0 statistical software to analysis data.Results:1.In HFrEF patients,the patients with deficiency of Yang Qi and blood stasis were more than those with Qi deficiency and blood stasis,Qi Yin and blood stasis;In patients with HFpEF,the patients with Qi deficiency and blood stasis,Yang Qi deficiency and blood stasis were more than those with Qi Yin deficiency and blood stasis.2.The prevalence of women in both types of heart failure patients was higher than that of men,and there was no statistically significant difference between the two groups after chi-square test(P>0.05).The average age of HFpEF patients was greater than that of HFrEF patients,and the difference was not statistically significant between HFrEF patients and three groups of patients with HFpEF(P>0 0.05).3.Compared with 6MWT of the same syndromes,the patients with HFrEF were more than HFpEF patients in Qi deficiency and blood stasis and Qi and Yin blood stasis,and the difference was statistically significant(P<0.05).In patients with two types of heart failure,the 6MWT of Qi deficiency and blood stasis and Qi Yin deficiency and blood stasis were both greater than those with deficiency and blood stasis of Yang Qi,and the difference was statistically significant(P<0.05).4.Compared with the same syndrome type of heart failure cESS,in the Qi deficiency and blood stasis type and Qi Yin deficiency and blood stasis type group,HFrEF patients were higher than HFpEF patients,and the difference was statistically significant(P<0.05).The MEE value of Yang Qi deficiency and blood stasis in two types of heart failure patients was higher than those of the other two types,and the difference was statistically significant(P<0.05).5.Logistic analysis of various TCM syndromes and corresponding indexes of HFrEF patients:Qi deficiency blood stasis was positively correlated with 6MWT and MEE,and was negatively correlated with LVSV.The blood stasis of Qi and Yin was positively correlated with 6MWT.Yang Qi deficiency blood stasis is related to LVSV,LVPWTs and cESS,which is negatively correlated with 6MWT and SBP.6.Logistic analysis of various TCM syndromes and corresponding indexes of HFpEF patients:Qi deficiency and blood stasis were negatively correlated with LVSV.The blood stasis of Qi and Yin was positively correlated with LVET and LVSV,and was negatively correlated with MEE.Yang Qi deficiency blood stasis is positively correlated with LVIDs.Conclusions:1.Among the patients with HFrEF,the patients with deficiency of Yang Qi and blood stasis were more than those with Qi deficiency and blood stasis,Qi Yin and blood stasis;Among the patients with HFpEF,the patients with Qi deficiency and blood stasis,Yang Qi deficiency and blood stasis were more than those with Qi Yin deficiency and blood stasis.2.HFrEF patients and HFpEF patients was higher in women than in men,The average age of HFpEF patients was greater than that of HFrEF patients.3.The six-minute walking distance was relative to the shortest in HFrEF patients and HFpEF patients of Yang Qi deficiency blood stasis type.4.HFrEF patients and patients with HFpEF had relative to the highest MEE.5.6MWT,MEE and LVSV,LVPWTs,cESS,SBP and other indicators may be objective indicators of TCM syndrome differentiation of HFrEF patients.6.LVET,LVSV and MEE and LVIDs may be the objective indicators of TCM syndrome differentiation in patients with HFpEF.