The Relationship Between Cat Periodontal Disease And Oral Flora And Its Prevention And Treatment

Periodontitis refers to a series of inflammatory lesions caused by dental plaque that damage the periodontal tissue and its supporting structures.It is a common chronic,non-communicable disease in feline.Cats with periodontitis often experience symptoms such as halitosis,salivation,pain,loss of appetite,loose and abnormal tooth loss,will seriously affect the quality of life.A large number of studies have shown that the dental plaque heap up on the surface of the teeth and under the gums is the main inducement of gingivitis and periodontitis.Oral flora is the second largest microbiota in animals.Microbes maintain homeostasis with their host.When pathogenic microorganisms multiply and break this balance,periodontitis can occur.At present,the research on cat periodontitis in China is relatively insufficient,and there is a lack of scientific prevention and control methods.Therefore,this study conducted an epidemiological survey on 126 adult cats to form the epidemiological data of feline periodontitis.9 healthy cats and 18 cats with periodontitis were selected.Collect samples from different areas in the oral of the two for microbial species identification.The collected samples were subjected to antimicrobial susceptibility test for commonly used antimicrobial drugs and commonly used antimicrobial agents in aerobic and anaerobic environments,respectively.Provide medication advice for clinical treatment.To evaluate the bacteriostatic effect of commonly used antibacterial agents after surgical cleaning,and provide a theoretical basis for the treatment of periodontitis in cats and home oral care.The main findings are as follows:1.Discovered through epidemiological investigations,Most animal owners lack awareness of their cats’ oral health,causes a higher incidence of periodontal disease in cats.Under the same oral care,age and dietary habits are high risk factors for periodontal disease in cats,Older cats and cats fed a high frequency of wet food are more prone to periodontal disease.2.In all cats tested,Subgingival microbial species abundance is higher than supragingival.The abundance of oral microbial species in cats with periodontitis is higher than that in healthy cats.Porphyromonas and Treponema are higher in subgingival than supragingival.As potential pathogenic microorganisms,it is speculated that they may be the key pathogenic factors of periodontitis.3.In vitro antimicrobial susceptibility test with Amoxicillin,Ampicillin,Cefalexin,Azithromycin,Doxycycline,Enrofloxacin and Metronidazole.Results showed that the oral microbiota of cats with periodontitis was more sensitive to Enrofloxacin and less sensitive to Metronidazole.In three oral care products with the Antimicrobial peptides,the Chlorhexidine gluconate and the Silver ion as the main components respectively,the Chlorhexidine gluconate and the Silver ion have better bacteriostatic effect.But the Chlorhexidine gluconate tastes bitter and has poor palatability for cats.It is recommended to be used as an oral antiseptic in surgery.In summary,factors such as older,higher frequency of wet food feeding are closely related to the incidence of periodontitis.Porphyromonas and Treponema may be the main pathogens of feline periodontitis.Enrofloxacin can be used as an empirical adjunctive therapy for feline periodontitis.It is recommended to use the Chlorhexidine gluconate in ultrasonic scaling,and to use the Silver ions after surgery.