A Brief Analysis Of The Medication Rules Of Traditional Chinese Medicine For The Treatment Of Bronchiectasis In Ancient And Modern Literature

Purpose: By sorting out the ancient and modern literature of bronchiectasis,obtaining the prescriptions and drugs used,and establishing databases of ancient and modern traditional Chinese medicine for treating bronchiectasis respectively,and performing drug efficacy classification,frequency statistics,association rules and cluster analysis processing,and analyzing and comparing ancient and modern traditional Chinese medicines for the treatment of bronchiectasis The law is expected to provide new ideas and references for clinical medication.Material and method : The source of ancient documents,through the search of "Chinese Medicine Dianhai" with "pulmonary carbuncle" and "hemoptysis" as keywords,222 prescriptions were screened out according to the inclusion and discharge criteria.Modern documents are searched through CNKI database,Wanfang database knowledge service platform database,and Weipu database as the search source.The first search is carried out with "bronchiectasis" and "pulmonary carbuncle" as the subject terms.On this basis,"Chinese medicine" is used.”,“Chinese Medicine” and “Chinese Medicine” were searched for a second time,and the literature published between January 2010 and December 2020 was selected,and 421 prescriptions were screened out according to the inclusion and exclusion criteria.Enter the selected prescriptions into the EXCEL table,and perform medication classification,frequency analysis,association rules and cluster analysis to analyze their prescriptions and medication rules.Results:1.The ancient literature contains 222 prescriptions,involving 229 kinds of medicines,and the total frequency of occurrence of medicines is 1867 times.The five most used drugs are,in order,phlegm,cough and asthma,tonic,heat-clearing,anti-surface,and diuresis and dampness.In addition to licorice,the top 10 most frequently used drugs are Platycodon grandiflorum,Chuan Fritillaria,Morus alba,Coix Seed,Angelica,Bitter Almond,Poria,Astragalus,Ginseng,and Ophiopogon.There were 17 groups of related drug pairs,and the highest support was Coix Seed-Licorice-Platoonflower and Chuan Fritillaria-Licorice-Platoonflower.The cluster analysis results can be divided into 4 groups.2.The modern literature contains 421 prescriptions,involving 316 types of drugs,and a total of 5192 occurrences of drugs.The five most used drugs are,in order,phlegm-relieving cough-asthmatic drugs,heat-clearing drugs,tonic drugs,hemostatic drugs,and diuretic and dampening drugs.In addition to licorice,the top 10 drugs with the most frequent use are Scutellaria baicalensis,Platycodon grandiflorum,Poria cocos,Mulberry bark,Coix seed,Houttuynia cordata,dried tangerine peel,Fritillaria,bitter almond,and Ophiopogon japonicus.There were 18 groups of related drug pairs,and the highest support was winter melon seed-coix seed,peach kernel-winter melon seed-coix seed.The cluster analysis results can be divided into 6 groups.Conclusion:1.Physicians in ancient and modern times believed that the basic pathogenesis of bronchiectasis was the deficiency and the deficiency,and the medicines were mainly used to relieve phlegm,relieve cough and relieve asthma,tonic,and to clear away heat.But on the basis of resolving phlegm,relieving cough and relieving asthma,ancient doctors tended to make up,and modern doctors tended to clear.In terms of drug compatibility,ancient and modern physicians have used diuresis and dampness medicine.In addition,ancient physicians also focused on anti-epidermic drugs,and modern physicians also focused on hemostatic drugs.2.From the clustering results,the ancient physicians unearthed four core prescriptions representing four treatment methods: resolving phlegm and relieving cough,clearing heat and replenishing deficiency,clearing heat and reducing lung,nourishing yin and replenishing blood,and replenishing qi and resolving phlegm.There are six core prescriptions of modern physicians,which represent the six treatment methods of resolving phlegm and clearing heat and removing blood stasis and purging pus,clearing heat and phlegm,cooling blood to stop bleeding,clearing heat and resolving phlegm and nourishing yin,replenishing qi and invigorating the spleen,and resolving phlegm and regulating qi..Discussing treatment from different angles can provide a certain reference for clinical practice.