Study On TCM Syndrome Types And Clinical Characteristics Of Newly Diagnosed Type 2 Diabetes Mellitus Patients With Metabolic Syndrome

Objective: To explore the correlation between the Syndrome of Chinese Medicine Types and clinical data in patients with newly-diagnosed type 2 diabetes and metabolic syndrome.So as to provide some references for the clinical diagnosis and prevention.Carry forward the unique advantages of Traditional Chinese Medicine in the prevention and treatment of chronic diseases.Methods:According to the case selection criteria choose patients in the inpatient department and the outpatient department of the Department of Endocrinology in the Changsha Hospital of Traditional Chinese Medicine Affiliated to Hunan University of Traditional Chinese Medicine(Changsha Eighth Hospital)from January 1,2019 to January 31,2021.Fill out the clinical questionnaires and perform the syndrome differentiation.Compare BMI,WC and other observation indexes between the groups.Multivariate Logistic regression was used to analyze the correlation between TCM syndrome types and the above indicators.Results:1.The frequency of syndrome distribution types in 292 patients from high to low is as follows:heat stagnation of liver and stomach syndrome(41.10%)、phlegm and blood stasis syndrome(20.55%)、qi Yin deficiency syndrome(16.78%%)、qi stagnancy and dampness-stagnation syndrome(10.27%)、 spleen-kidney qi deficiency syndrome(4.45%)、liver-gallbladder damp-heat syndrome(3.77%)、spleen deficiency and phlegm turbidity syndrome(3.08%).2.Among the 292 patients,the majority were men,accounting for 69.52%.3.Among the 292 patients,patients with spleen-kidney qi deficiency syndrome were the oldest,with an average age of 55.46±10.32 years old,the age difference was statistically significant,and were related to patients with heat stagnation of liver and stomach syndrome,liver-gallbladder damp-heat syndrom,spleen deficiency and phlegm turbidity syndrome,qi stagnancy and dampness-stagnation syndrome.4.Among the 292 patients,the TC and LDL of patients with heat syndrome were higher than those of patients with non-heat syndrome,P<0.05,and the difference was statistically significant.5.Among the 292 patients,the UACR level of heat syndrome patients were lower than those of patients with non-heat syndrome,P=0.03,the difference was statistically significant.Grouping the UACR shows that the UACR levels of patients with heat syndrome were mostly normal(UACR<30mg/g),accounting for 64.89%,and most patients in the non-heat syndrome group had proteinuria(UACR ≥ 30mg/g),accounting for 56.52%.P=0.00,the difference was statistically significant.6.Among the 292 patients,most of the patients’ 25(OH)D levels were in a state of insufficiency and deficiency [25(OH)D≤75nmol/L],accounting for 99.00%.7.Multivariate logistic regression analysis showed that age,UACR,AIP were correlated with syndrome types.And got the regression equation:Logit(P)= 3.993-0.840×Age1(<45)-0.865×UACR1(<30)-1.070×AIP1(<0.1)。Conclusion:1.Newly diagnosed T2 DM patients with MS mainly have the syndrome of heat stagnation of liver and stomach syndrome.Patients with spleen-kidney qi deficiency syndrome are the oldest.2.Newly diagnosed T2 DM patients with MS generally suffer from 25(OH)D deficiency and deficiency.3.Non-heat syndrome group have a high risk of proteinuria.4.For newly diagnosed T2 DM patients with MS,as the age,UACR and AIP levels increase,the greater the possibility of non-heat syndrome.