| Objective: to investigate the correlation between sublingual vein score and liver cirrhosis stage and fibrotouch.Objective to clarify the relationship between sublingual vein and the progression of liver cirrhosis and liver stiffness,so as to provide some basis for early evaluation of liver cirrhosis and dynamic monitoring of disease changes.Methods: The outpatients and inpatients in the First Hospital of Hunan University of Chinese Medicine were selected to sign informed consent.According to the clinical observation table,the basic information,symptoms,signs,tongue and pulse,blood routine,liver function and liver hardness of the patients were recorded.The images of sublingual vein were transferred to the computer and numbered,and saved in a unified format.The length and width of sublingual vein were calculated by Adobe Photoshop software,and the sublingual vein of each patient was scored from the color purple dark,trunk branch,trunk filling degree,degree of varicose,sublingual collateral,sublingual spot,length and width.Spss26.0 software was used to analyze the collected data.Results:1.A total of 90 patients were included in this study,including 66 males and24 females;the ratio of male to female in hepatitis group was 1.92:1,compensated group was 4.83:1,decompensated group was 2.33:1,in the three groups of patients,the gender difference was not statistically significant(P > 0.05),the difference between the ages was statistically significant(P < 0.05)2.The sublingual vein score of hepatitis group was 13.77±1.98,that of compensatory group was 16.69±3.79,and that of decompensated group was 19.40±3.12.The difference of sublingual vein score among the three groups was statistically significant(P<0.05).After pairwise comparison,the sublingual vein score of decompensated group was significantly higher than that of compensatory group and hepatitis group It was significantly higher than that in hepatitis group.The sublingual vein score was positively correlated with the progression of liver disease(r = 0.585,P< 0.01).From chronic hepatitis B to compensated and decompensated liver cirrhosis,sublingual collaterals score increased gradually.3.The liver stiffness was 9.33±2.49 kpa in hepatitis group,12.80±2.94 kpa in compensated group and 17.46±6.41 kpa in decompensated group.The difference of liver stiffness in three groups was statistically significant(P < 0.05).After pairwise comparison,the liver stiffness in decompensated group was significantly higher than that in compensated group and hepatitis group,and in compensated group it was significantly higher than that in hepatitis group.There were significant differences in the APRI index among the three groups(P < 0.05).Through further pairwise comparison,the APRI index of patients in decompensated stage were significantly higher than those in compensated stage and hepatitis group.4.There was a positive linear correlation between sublingual vein score and liver stiffness in three groups,with correlation coefficient r = 0.709,P < 0.05;through statistical analysis,the correlation coefficients of sublingual vein score and liver hardness value in hepatitis group,compensated group and decompensated group were0.586,0.572 and 0.630(P < 0.05).There was a positive linear correlation between liver stiffness and APRI index in three groups,the correlation coefficient was 0.614(P< 0.05).After statistical analysis,in the hepatitis group and the compensated group,the correlation between APRI index and liver stiffness was statistically significant(P > 0.05).In the decompensated group,the correlation coefficient between APRI index and liver stiffness was 0.515(P < 0.05).Conclusion: There were significant differences in sublingual vein score and liver stiffness among hepatitis group,compensated cirrhosis group and decompensated cirrhosis group.With the aggravation of liver disease,the higher sublingual vein score,the higher liver stiffness.As a non-invasive method,sublingual vein score can be used to evaluate early cirrhosis and dynamically monitor the changes of the disease,which can be further promoted in clinic. |
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