| Research Purpose:This study aims to explore the effects of transcendental meditation training on the perioperative stress response of gastric cancer patients,and provide a scientific basis for perioperative transcendental meditation training in clinical application.Research Methods:According to the randomized controlled trial,from April 2021 to December 2021,60 patients with gastric cancer who underwent laparoscopic radical gastrectomy in gastrointestinal surgery of a tertiary general hospital in Huzhou,Zhejiang Province were selected according to the inclusive criteria.The patients were enrolled according to the order of admission,with 30 cases in the control group and 30 cases in the experimental group.During the perioperative period,the control group was given routine psychological nursing and resting,while the experimental group was given routine psychological nursing and transcendental meditation training.The patients’ general information and surgical stress index data（state anxiety score,pain,blood pressure,heart rate,blood glucose,C-reactive protein,white blood cell count,complications）were collected.Statistical analysis of the data was performed using SPSS 23.0 software,with P<0.05 as the test standard.Research Results:1.Baseline comparison:The age,gender,cultural level,marriage,form of payment,monthly income,occupation,operation mode,disease stage and anastomosis mode of the two groups were compared at baseline.The results showed no statistical difference（P>0.05）.The baseline comparison analysis of state anxiety score,pain,systolic blood pressure,diastolic blood pressure,heart rate,blood glucose,C-reactive protein,and white blood cell count between the two groups of research subjects showed that there was no statistical difference（P>0.05）.2.State anxiety score:①Comparison between groups:There was no statistically significant difference in baseline the day before operation（T0）between the experimental group and the control group（P>0.05）.On the fifth day after operation（T3）,the state anxiety scores of the experimental group and the control group were compared,and the results were statistically different（P<0.05）.The state anxiety score of the experimental group was lower than that of the control group.The difference between the two groups before and after the intervention showed that the results were statistically significant（P<0.05）,and the experimental group was significantly lower than the control group.②Intra-group comparison:the experimental group and the control group were compared in each group,the differences were statistically significant（P<0.05）,and the state anxiety score on the fifth day after operation was lower than that on the first day before operation.3.Pain score:（1）Comparison between groups:there was no significant difference in baseline between the experimental group and the control group the day before operation（P>0.05）.There was no significant difference between the two groups on the first day and the third day after operation（P>0.05）.There was a significant difference between the two groups on the fifth day after operation（P<0.05）.The difference between the preoperative day（T0）and the fifth day after operation（T3）was statistically significant（P<0.05）.（2）Comparison within groups:the pain scores of each group at different time points were statistically significant（P<0.05）.Pairwise comparisons were carried out in each group:①Experimental group:pain score at different time points pairwise comparison were statistically significant（P<0.05）.②Control group:pain score at different time points pairwise comparison were statistically significant（P<0.05）.4.Blood pressure:（1）Systolic blood pressure:①Comparison between groups:there was no significant difference in the baseline of systolic blood pressure at T0 between the experimental group and the control group（P>0.05）.There was a significant difference in systolic blood pressure at T3 between the two groups（P<0.05）.The systolic blood pressure value of the experimental group was lower than that of the control group.The difference in systolic blood pressure between the two groups before and after intervention was statistically significant（P<0.05）,and the value of the experimental group was higher than that of the control group.②Intra group comparison:the differences in intra-group comparison were statistically significant（P<0.05）,and the systolic blood pressure at T3 was lower than that at T0.（2）Diastolic blood pressure:①Comparison between groups:there was no significant difference in the baseline of diastolic pressure at T0 between the experimental group and the control group（P>0.05）.There was a significant difference in diastolic blood pressure at T3 between the two groups（P<0.05）.The diastolic blood pressure value of the experimental group was lower than that of the control group.The diastolic blood pressure difference between the two groups before and after the intervention was compared,and the result showed that there was a statistical significance（P<0.05）,and the value of the experimental group was higher than that of the control group.②Intra group comparison:the differences in intra-group comparison were statistically significant（P<0.05）,and the diastolic blood pressure at T3 was lower than that at T0.5.Heart rate:①Comparison between groups:there was no significant difference in the baseline of heart rate at T0 between the experimental group and the control group（P>0.05）.There was a significant difference in heart rate at T3 between the two groups（P<0.05）.The heart rate of the experimental group was lower than that of the control group.The heart rate difference between the two groups before and after the intervention was compared,and the result showed a statistical significance（P<0.05）,and the experimental group was higher than the control group in numerical value.②Intra group comparison:there were statistically significant differences among groups（P<0.05）,and the heart rate at T3 was lower than that at T0.6.Blood glucose:（1）Comparison between groups:there was no significant difference in the baseline of blood glucose at T0 between the experimental group and the control group（P>0.05）;there was no significant difference in heart rate between the two groups at T1,T2 and T3（P>0.05）.The comparison of difference values before and after intervention showed that the difference values of T0 and T1,T0 and T2,T0 and T3 were not statistically significant（P>0.05）.（2）Comparison within groups:the differences in blood glucose values at different time points of each group were statistically significant（P<0.05）.Pairwise comparisons were made in each group:①Experimental group:Except that there was no significant difference in blood glucose between T0 and T1（P>0.05）,the blood glucose values at different time points were statistically significant（P<0.05）.②Control group:Except that there was no significant difference in blood glucose between T0 and T1,and between T2 and T3（P>0.05）,the blood glucose values were statistically significant at different time points（P<0.05）.7.C-reactive protein:（1）Comparison between groups:there was no significant difference in the baseline of C-reactive protein at T0 between the experimental group and the control group（P>0.05）.There was no significant difference in C-reactive protein between the two groups at T1,T2 and T3（P>0.05）.The comparison of difference values before and after intervention showed that the difference values of T0 and T1,T0 and T2,T0 and T3 were not statistically significant（P>0.05）.（2）Comparison within groups:The difference of C-reactive protein at different time points in each group was statistically significant（P<0.05）.Pairwise comparisons were performed in each group:①Experimental group:C-reactive protein at different time points pairwise comparison were statistically significant（P<0.05）.②Control group:C-reactive protein at different time points pairwise comparison were statistically significant（P<0.05）.8.White blood cell count:（1）Comparison between groups:There was no significant difference in the baseline of white blood cell count at T0 between the experimental group and the control group（P>0.05）.There was no significant difference in white blood cell count between the two groups at T1,T2 and T3 time points（P>0.05）.The comparison of difference values before and after intervention showed that the difference values of T0 and T1,T0 and T2,T0 and T3 were not statistically significant（P>0.05）.（2）Comparison within groups:The differences in white blood cell count at different time points in each group were statistically significant（P<0.05）.Pairwise comparisons were made in each group:①Experimental group:Except that there was no statistically significant difference in white blood cell count between T0 and T2（P>0.05）,white blood cell count was statistically significant at different time points（P<0.05）.②Control group:Except that there was no statistically significant difference in white blood cell count between T0 and T3（P>0.05）,white blood cell count was statistically significant at different time points（P<0.05）.9.Complications:There were no other complications in the experimental group and the control group.There was no significant difference in the incidence of lower extremity venous thrombosis and infection between the two groups（P>0.05）.Research Conclusion:Transcendental meditation training has a certain effect on improving the perioperative stress response of gastric cancer patients.It can relieve the anxiety of gastric cancer patients during the perioperative period,and at the same time,it can also effectively reduce the perioperative pain,reduce the perioperative blood pressure,slow down the heart rate.It has no significant effect on improving blood glucose and inflammatory indicators（C-reactive protein,white blood cell count）,and complications,and further research is needed.Transcendental meditation training,as a green,environmentally friendly,simple and easy-to-operate psychological relaxation training technique,has a satisfactory overall effect and good feasibility in the perioperative period of gastric cancer patients,and can be popularized and used in the clinical perioperative period. |
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