Clinical Observation And Rs-fMRI Study On Acupotomy In The Treatment Of Acute Paroxysmal Vertigo

Objective: by using magnetic resonance imaging(functional magnetic resonance imaging)technology to observe small needle knife therapy vestibular peripheral vertigo brain function in patients with acute phase change,for this small needle knife therapy vestibular peripheral vertigo provides the preliminary basis for the mechanism of action of acute phase,as well as the clinical use of small needle knife therapy provide theoretical support around the vestibular vertigo.Methods: 22 patients with acute para-vestibular vertigo who met the inclusion criteria were randomly divided into acupotomology group(treatment group)and drug group(control group)using SAS statistical software.Those in the drug group were enrolled directly into the drug group,those in the acupotomology group were enrolled into the acupotomology group after informed consent,and those who disagreed were enrolled into the drug group.The changes of the vertigo rating system(DARS)before treatment,5 min,30 min,2h,6h,and 24 h and the changes of subjective vertical vision(SVV)at 3d and 6d after treatment were observed in the treatment group and the control group.Statistical analysis was performed according to the data results.Results:(1)the total DARS scores of the experimental group before treatment and after treatment at 5min,30 min,2h,6h and 24 h were compared,and the differences were statistically significant(P < 0.05).(2)compared with the control group before treatment and 5min-2h after treatment,the difference was not statistically significant(P > 0.05),while the difference was statistically significant(P < 0.01)in each time window after treatment and before treatment(P < 0.01).(3)compared with the baseline data of the control group,P > 0.05 was considered to be comparable.(4)total score of DARS before treatment and comparison between the two groups.P > 0.05,proving comparability.(5)in patients with acute para-vestibular vertigo,signals increased correspondingly in the functional areas of the brain,including the superior temporal gyrus,middle temporal gyrus,medial frontal gyrus,inferior parietal lobule and posterior central gyrus,when compared with the normal control group during fMRI examination;The above areas are activated areas,and the corresponding brain areas with decreased signal include: inferior temporal gyrus,superior temporal gyrus,insula,basal ganglia,thalamus,frontal cortex,precuneus,anterior cingulate gyrus,etc.The above areas are negative activation areas.Conclusion:1.For vestibular vertigo patients with acute attack characteristics of traditional Chinese medicine to give small needle knife therapy can relieve the vertigo and accompanying symptoms,giving oral diphenhydramine treatment,patients can effectively patients and the accompanying symptoms of dizziness,vestibular peripheral vertigo after needle knife therapy acute vestibular symptoms improve,dizziness can alleviate superior to drug group;2.The onset time of acupotomology was basically within 5min,and the improvement of symptoms was found to be in a continuous and stable state with the extension of the observation time window;If there is no significant improvement in the patient’s symptoms within 5 minutes,the patient’s vertigo symptoms will not be further alleviated with time.It shows that the effect of acupotomology is rapid and stable.3.In patients with acute episode of perivestibular vertigo(fMRI),the corresponding excited areas include superior temporal gyrus,middle temporal gyrus,medial frontal gyrus,subparietal lobule and posterior central gyrus.These brain regions may be associated with the acute onset of perivestibular vertigo.