Correlation Analysis Of Thrombosis Therapy In Different Time Window For Acute Cerebral Infarction

Objective: To investigate the correlation between the efficacy of venous thrombosis in patients with acute cerebral infarction in different time windows.Methods: Retrospective analysis of the 185 patients admitted to the Department of Neurology of Jilin Provincial People’s Hospital from March 2017 to December 2019 to recover their neurological function,divided into 3 groups according to the time window: 71 patients with venous thrombosis within 2 hours(including 2 hours)47 patients with venous thrombosis within 2-3 hours(including 3 hours)and 67 patients with venous thrombosis within 3-4.5 hours,respectively,recorded the pre-solution,24 hours after the pre-solution,7days after the pre-solution thrombosis,14 days after the thrombosis,and 14 days after the pre-solution thrombotic,and 14 days after the intravenous thrombosis,respectively,the PATIENTs were recorded.The correlation of efficacy after intravenous thrombosis was analyzed in three groups of patients with acute cerebral infarction.The SPSS-related analysis is used for statistical analysis.Results:1.Effective indicator comparison:(1)Comparison of NIHSS scores: 24 hours before and after the 2-hour thrombosis group,the median difference of NIHSS score for 7 days is 2(1,5),3(1,6),and 24 hours before and after the 2-3 hour venous thrombosis group,The 7days,median value of NIHSS scoring differences was compared with median 1(0,3),2(1,4),the difference was statistically significant(P <0.05);(2)THE median of the MRS score difference for 90 days before and after the 2-hour thrombosis group was 2(1,3),Compared with the median MRS score difference of 1(0.25,2),1(1,2)for 90 days before the 2-3 hour thrombotic group and 3-4.5 hour thrombotic group,the difference was statistically significant(P<0.05);(3)a comparison of the 90-day good prognosis rate:comparison of the 2-hour thrombosis The 90-day good prognosis rates for the 3-4.5-hour thrombotic group were: 95.14%(65/71),65.67%(44/67),and the differences between them were statistically significant(P=0.001,<0.05).2.Comparison of safety indicators: The overall mortality rate was 2.82%(2/71),4.26%(2/47),4.48%(3/67)for patients in groups 3 of 90 days,respectively,and the overall mortality rate in the 3 groups was close,with no statistically significant difference(P>0.05).Conclusion:1.The earlier AIS patients carry out venous thrombosis,the better the clinical efficacy,the better the recovery of nerve function;2.There was little change in the overall mortality rate of patients with venous thrombosis in the effective time window.