Clinical Observation Of En Bloc Transurethral Resection Of Bladder Tumor Combined With Tumor Submucosal Injection Of Pirarubicin

ObjectiveTo evaluate the efficacy of en bloc transurethral resection of bladder tumor combined with tumor submucosal injection of pirarubicin in the treatment of non muscle-invasive bladder cancer.MethodsThe clinical data of 80 cases with NMIBC treated with endoscopic surgery during January 2017 to June 2018 were analyzed retrospectively.Age 31-89 years old,average(68.1 ± 14.8)years old.we review all patients were randomly divided intotwo groups,one ofgroup is en bloc transurethral resection of bladder tumor combined with tumor submucosal injection of pirarubicin.another group is TURBt.and record two groups of general information,operation time,tumor size,hospitalization time,tumor recurrence rate.The data were processed by using SPSS 20.0,the results were expressed as mean ± standard deviation,and the independent sample t-test was used and compare the count data using a chi-square test.There is a statistically significant(P<0.05),there is no statistical difference(P > 0.05).Results80 cases were treated with surgery,statistical results,The operation time(min): experimental group:(52.08±18.08)min,control group:(42.18±11.52)min,the difference between the two groups was considered statistically significant(P<0.05);Postoperative bladder irrigation time(h): experimental group:(13.24 ± 1.71)h;control group:(29.12 ±3.43),statistically significant difference between the two groups(P <0.05);Indwelling time of catheter(d): experimental group:(4.20±0.91)d,control group(4.64±1.32)d,there was no statistical difference between the two groups(P>0.05);Hospitalization time(d)Experimental group:(7.18±2.08)d,control group:(8.05±1.94)d;There were statistically significant(P<0.05);The number of postoperative tumor recurrences during the follow-up period: experimental group: 2/40(5.00%),control group: 11/40(27.50%),statistically there were significant difference between the two groups(P<0.05).ConclusionIn treating NMIBC,en bloc transurethral resection of bladder tumor combined with tumor submucosal injection of pirarubicin,compared with TURBT: Postoperative bladder irrigation timeis short;The tumor recurrence rate can be reduced.