Clinical Study On "Shuanggu Yitong" Acupuncture Combined With Yijinjing Function In The Treatment Of Climacteric Syndrome

ObjectiveTo observe the clinical efficacy of "Shuanggu Yitong" acupuncture method and "Shuanggu Yitong" acupuncture method combined with Yijinjing function method in the treatment of climacteric syndrome（PMS）,and explore its mechanism,so as to affirm the clinical efficacy advantages of "Shuanggu Yitong" acupuncture combined with Yijinjing function method in the treatment of climacteric syndrome,and provide new ideas for enriching the treatment methods and treatment schemes of clinical climacteric syndrome.Methods34 patients with climacteric syndrome who met the inclusion criteria were randomly divided into acupuncture group and acupuncture combined with Yijinjing group,with 17 patients in each group.The acupuncture group was treated with "Shuanggu Yitong" acupuncture method.On the basis of taking Zusanli（bilateral）,Guanyuan,Sanyinjiao（bilateral）,Taixi（bilateral）,Shenmen（bilateral）and Taichong（bilateral）as the main points,the patients with atypical syndrome types were treated with the main points,and then added and subtracted with the patients’ symptoms（added and subtracted with the symptoms: hot flashes and night sweats increased refluxing and Hegu;insomnia increased Baihui and Shenmai）;The main points of kidney yin and sea deficiency increased;The main points of kidney yang deficiency syndrome increase the vital gate and Zhiyang;Main points of hyperactivity of liver Yang+ Gan Shu and inter line;Phlegm stagnation,Yin Ling spring and Fenglong;Increase and decrease with symptoms: hot flashes and night sweats increase,refluxing and valley closure;Insomnia increases Baihui and Shenmai;Three times a week,four weeks as a course of treatment,a total of two courses of treatment;On the basis of "Shuanggu Yitong" acupuncture and Yijinjing exercise,the acupuncture combined with Yijinjing group exercised at least three times a week,about 40 minutes each time,three times a week.The end of four weeks was one treatment cycle,with a total of two courses of treatment.The modified Kupperman index score（hereinafter referred to as modified ki score）,perimenopausal quality of life（menqol）scale score,Pittsburgh sleep quality（PSQI）scale score and serum follicle stimulating hormone（FSH）level of the two groups were recorded before admission and 8 weeks after treatment.Two laboratory tests were conducted and the results were recorded at the time of admission and exit.Results1.Comparison of improved ki score: the improved ki score of the two groups decreased after 8 weeks of treatment,and the difference was statistically significant（P < 0.05）.2.The symptom scores of the two groups decreased after 8 weeks of treatment,and the difference was statistically significant（all P < 0.05）.After 8 weeks of treatment,the improvement of symptoms such as sensory abnormalities,depression,suspicion and bone and joint pain in the acupuncture combined with Yijinjing group was better than that in the simple acupuncture group（all P < 0.05）;There was no significant difference in the improvement of hot flashes,night sweats,sexual life,reproductive and urinary system between the two groups（all P > 0.05）.3.Comparison of menqol scores between the two groups before and after treatment: the menqol scores of the two groups decreased after 8 weeks of treatment,and the difference was statistically significant（P < 0.05）.The menqol score of acupuncture combined with Yijinjing group was better than that of simple acupuncture group after 8 weeks of treatment(P.4.Comparison of PSQI scores between the two groups before and after treatment: the PSQI scores of the two groups decreased after8 weeks of treatment,and the difference was statistically significant（P < 0.05）.The PSQI score of patients treated with acupuncture combined with Yijinjing exercise was significantly higher than that of patients treated with simple acupuncture（P >0.05）.5.Comparison of serum sex hormone FSH levels between the two groups before and after treatment: there was no significant difference in serum FSH levels between the two groups after treatment and before treatment（all P > 0.05）.6.Comparison of comprehensive curative effect: according to the ki score,the total effective rate of the treatment group was93.33%,and that of the control group was 86.67%.The difference was statistically significant（P < 0.05）,indicating that the clinical curative effect of acupuncture combined with Yijinjing exercise group was better than that of simple acupuncture group.7.Comparison of adverse reactions between the two groups: 1patient in the simple acupuncture group had mild subcutaneous blood stasis,and the total adverse reaction rate was 6.67%;During the treatment of acupuncture combined with Yijinjing group,one patient had mild subcutaneous blood stasis,and the total adverse reaction rate was 6.67%.There was no significant difference in the incidence of total adverse reactions between the two groups（P > 0.05）.Conclusion1."Shuang Gu Yi Tong" acupuncture and "Shuang Gu Yi Tong" acupuncture combined with Yijinjing exercise are effective in the treatment of climacteric syndrome.2."Shuanggu Yitong" acupuncture combined with Yijinjing group is more effective than "Shuanggu Yitong" acupuncture alone in the treatment of emotional disorders,muscle,bone and joint pain,fatigue and other symptoms.3."Shuanggu Yitong" acupuncture combined with Yijinjing group has better comprehensive effect and better long-term effect.4."Shuanggu Yitong" acupuncture and "Shuanggu Yitong" acupuncture combined with Yijinjing exercise have less adverse reactions and high safety in the treatment of climacteric syndrome.