The Study Of TCM Constitution And Clinical Manifestations Of 360 PCOS Patients

Objective Through the collection of 360 cases of polycysticovarysyndrome(PCOS)Patients with TCM constitution and clinical symbtoms related information,further summarized the PCOS patients’ constitution tybe and clinical symbtoms,conducive to the Prevention and treatment of PCOS,can provide ideas for clinical research.MethodThis study is a cross-sectional study.The subjects are 360 PCOS patients who met the requirements of the study and went to the gynecological outpatient department of the First Affiliated Hospital of Guangzhou University of Chinese Medicine from October,2017 to October,2018.The survey method was questionnaire survey.Information collected :(1)General information such as age,height and weight;(2)Menstruation and accompanying symptoms;(3)Acne and hirsutism;(4)Uterine double adnexa color ultrasound and basic endocrine detection and other auxiliary examinations;Professor Wang Qi’s nine-point constitution method was used to identify their constitutions.The collected data were summarized and analyzed by Excel.2010 and SPSS25.0.Result1.Distribution of TCM constitution types:The number of patients with Qi deficiency 63 cases(17.5%),phlegmy wet 60 cases(16.67%),Yin deficiency54cases(15%),Yang deficiency 48 cases(13.33%),and Mild constitution 39 cases(10.83%),Qi depression 39 cases(10.83%),blood stasis 27 cases(7.5%),Hygrothermal 18 cases(5%),Special quality 12 cases(3.33%).2.In terms of BMI:(1)59.72% of the patients are normal weight,15.56% are underweight(BMI<18.5)and24.72% were obese(BMI≥24);(2)There is a significant positive correlation between phlegmy wet and BMI(P<0.01),suggesting that obese people are more common in phlegmy wet people;(3)There is a negative correlation between special quality and Yang deficiency quality and BMI(P<0.01,P<0.05),indicating normal body type or lean body type.3.In terms of WHR:29.44% of patients with WHR≥0.8 and 70.56% with WHR<0.8;WHR≥0.8 is more common in phlegmy wet,and there is a significant correlation with WHR(P<0.05),indicating that WHR≥0.8 is common in phlegmy wet.4.In terms of Menstrual Symptoms:(1)There is a negative correlation between Yang deficiency and waist acid(P=0.00<0.05);(2)Qi depression is negatively correlated with menstrual cycle,color,texture,dysmenorrhea and breast swelling pain(P<0.05);(3)Blood stasis is positively correlated with menstrual volume,texture,blood clots,menstrual period and breast pain(P<0.05),which was characterized by heavy menstrual volume,blood clots,long menstrual period and breast pain;(4)Mild constitution is positively correlated with blood clots,waist acid,menstrual volume,etc.,and negatively correlated with subband and dysmenorrhea(P<0.05).(5)There is a positive correlation between phlegmy wet and dysmenorrhea(P=0.02<0.05),which was often characterized by dysmenorrhea.(6)Qi deficiency is positively correlated with dysmenorrhea and breast pain(P<0.05),showing dysmenorrhea and breast pain;(7)There is a positive correlation between special quality and lumbar acid(P<0.05),which is accompanied by the symptoms of lumbar acid.5.In terms of acne:There is a significant positive correlation between phlegmy wet,Mild constitution and acne(P<0.05),which showed multiple acne.6.There is a significant positive correlation between Hygrotherma and Qi depression and hirsutism(P<0.05),and hirsutism was observed in both groups.7.In terms of bite and sup:(1)There is a significant positive correlation between mild quality and light diet(P=0.00<0.01);(2)There is a significant Positive correlation between phlegmy wet and greasy diet(P=0.00<0.01);(3)There is a significant positive correlation between Qi-deficiency and raw and cold diet(P=0.00<0.01);(4)There is a significant positive correlation Between Yin deficiency and spicy diet(P=0.00<0.01).8.In terms of sex hormones(1)The proportion of Patients with higher prolactin level than normal was 17.78%;Hyperprolactinemia was more common in patients with Blood stasis(33.33%),Qi depression(30.77%)and special quality(25%);(2)The Proportion of LH/FSH≥2 was 61.67%;LH/FSH≥2 was more common in Qi deficiency(79.37%),Hygrothermal(77.78%)and special quality(75%)constitutive types.The value of LH/FSH was positively correlated with special quality(P<0.05);(3)The blood stasis and Yin deficiency are significantly correlated with androgen(P<0.05),suggesting that the two bodies were accompanied by high male sex hormone.Conclusion1.Qi-deficiency,phlegm wet and yin-deficiency may be the favorable constitution of PCOS patients;2.Patients with Qi deficiency are often accompanied by dysmenorrhea,breast distention and pain during menstruation;More raw and cold diet.3.Patients with phlegmy wet are usually obese,with high waist-hip ratio and accompanied by acne,dysmenorrhea,and eat more greasy food;4.Patients with Hygrothermal are often accompanied by hirsutism;5.Patients with blood stasis often have prolonged menstrual period,Menstrual quantity is too much,menstrual texture is too thick,accompanied by blood clots,easy to appear Breast swelling pain symptoms;High androgen is found;6.Patients with Qi depression are often accompanied by dysmenorrhea and hirsutness;7.Mild constitution common waist acid,more menstrual volume,accompanied by blood clots,acne,more light diet;8.Patients with Yin deficiency are often accompanied By high male sex hormones and spicy diet;9.LH/FSH≥2 was more common in patients with special quality,and most patients were accompanied by waist acid.