| This thesis is divided into two parts.The first part is a literature review,including the research progress of the theory of phlegm and blood stasis in traditional Chinese medicine and modern medicine of coronary heart disease,as well as the introduction of "Chang’an Lei’s heart disease phlegm and blood stasis school" and three main academic thoughts.,Etiology,pathogenesis,outcome,and modern doctors’ understanding of it.Summarize the theory of phlegm and blood stasis,and summarize the understanding and treatment of coronary heart disease in modern medicine,including risk factors,medications,and other treatments.Finally,a brief introduction to the genre Organizational structure and main academic thoughts.The second part analyzes the "Chang’an Lei’s Heart Disease Phlegm and Blood Stasis School" and the clinical experience and medication rules of members of the school in the diagnosis and treatment of coronary heart disease and angina pectoris through the TCM inheritance auxiliary platform,including syndrome differentiation,commonly used prescriptions,commonly used drugs and drug pairs,drug characteristics,and core Drugs and their additions and subtractions;the commonly used drugs and core drugs of genre for the treatment of phlegm and blood stasis syndrome of chest obstruction and heartache;similarities and differences of experience between genres and genre members.ObjectiveEstablish the "Chang’an Lei’s Heart Disease Phlegm and Blood Stasis School" for the diagnosis and treatment of coronary heart disease and angina pectoris patients with TCM clinical diagnosis and treatment database,and summarize the clinical experience and medication rules of members of the schools and schools in order to inherit their academic ideas and explore possible changes in the school’s inheritance.MethodWith the aid of the traditional Chinese medicine inheritance platform,this study collected medical record data from patients with coronary heart disease and angina pectoris diagnosed and treated by Lei Zhongyi,the founder of the "Changan Lei’s Heart Disease Phlegm and Stasis School" and inheritors with clear inheritance trajectories,and conducted a retrospective study.Enter the standardized qualified medical records into the platform,and use the software’s own statistical reports and data analysis functions to extract common syndrome types,high-frequency drugs,common prescriptions and drug pairs,and core drugs for the treatment of coronary heart disease and angina pectoris.Clinical experience and medication rules.ResultsThis study collected 911 patients with coronary heart disease and angina pectoris who met the inclusion criteria,of which 49.08% were males and 50.92% were females.The youngest patients were 20 years old,the oldest was 90 years old,and those over 60 years old accounted for 58.45%,with a total of 1408 cases.,Including 1408 prescriptions,including 323 cases of Master Lei Zhongyi,429 cases of Chief Physician Liu Chaofeng,419 cases of Chief Physician Zhang Junru,and 237 cases of other members of the school.A total of 280 Chinese medicines were used.Commonly used syndrome types: The schools are often divided into phlegm and blood stasis,qi stagnation and phlegm resistance,qi deficiency and blood stasis,qi stagnation and blood stasis,qi deficiency and blood stasis,qi and yin deficiency and blood stasis,qi and yin deficiency and internal resistance of phlegm and blood stasis,and phlegm,blood stasis and poison.Syndrome types are used to treat coronary heart disease angina pectoris,and the frequency of Qi deficiency and blood stasis,Qi and Yin deficiency with internal resistance of phlegm and blood stasis,Qi and Yin deficiency and blood stasis syndrome are significantly increased in Lei Lao’s syndrome differentiation,ranking second to fourth.Mention;Liu Chaofeng and Zhang Junru chief physicians have roughly the same frequency of card types.It can be seen that the first type of syndrome is the mutual syndrome of phlegm and blood stasis,which is related to the characteristics of the school.Lei Laoyou pays attention to the deficiency of coronary heart disease and angina pectoris.Stagnation of phlegm obstruction syndrome.Commonly used prescriptions: Lei Lao often used self-developed prescriptions such as Yangxin Huoxue Decoction,Lei’s Danlou Decoction,Danqu Decoction,Liu Shi flexibly added and reduced Xuefu Zhuyu Decoction to make his own Wuzhuyu Decoction,and the instructor was good at using such as Xiao Chaihu Decoction,Sini San,Banxia Houpu Decoction,Zhenwu Decoction and other classic prescriptions,self-made Sini San and Danqi Shengmai Decoction.High-frequency drugs: A total of 280 kinds of drugs are used in the school,and the top ten drugs include Salvia miltiorrhiza,Trichosanthes,Chuanxiong,Bupleurum,Citrus aurantium,Qing Pinellia,Scallion White,Red Peony Root,and Coptis chinensis.Lei Lao uses 232 kinds of drugs.Salvia miltiorrhiza,Ophiopogon japonicus,Schisandra chinensis,Panax notoginseng powder,astragalus,tangerine peel,scallion white,trichosanthes,coptis,and kudzu root are the top ten drugs respectively.Shi Liu uses 170 kinds of drugs.The top ten drugs include Trichosanthes,Qing Pinellia,Bupleurum,Coptis,Red Peony Root,Salvia Miltiorrhiza,Astragalus,Chuanxiong,Fructus Aurantii,and Guizhi.The tutor used180 kinds of drugs,and the top ten drugs were Bupleurum,Citrus aurantium,Salvia miltiorrhiza,Chuanxiong,Poria,Fructus Trichosanthis,Stir-fried White Peony,Qing Pinellia,Scallion White,and Achyranthes Bidentata.The top ten drugs used in the syndrome of phlegm and blood stasis include Gualou,Salvia,Chuanxiong,Scallion White,Qing Pinellia,Bupleurum,Astragalus,Red Peony,Citrus aurantium,Coptidis.Commonly used drug pairs: Common medicine pairs for Lei Lao include: red peony root and Dalbergia odorifera;bergamot,turmeric and Cyperus rotundus;lily,anemarrhena and rehmannia glutinosa;Piper longum and galangal;Eupatorium and Chinensis.Master Liu often used Chinese neem seed and Corydalis,Gynostemma pentaphyllum and raw hawthorn,Acorus calamus and amber,and bitter participation Gansong and other medicines.Common medicine pairs used by instructors include: Prince Edward participates in astragalus;Bupleurum and Roasted White Peony;Bupleurum and Citrus aurantium;Cyperus odoratus,Turmeric and Albizia Bark;Citrus aurantium,Platycodon and Magnolia officinalis;Caulis spatholobi and Trachelospermi Caulis;Danshen,Chuanxiong and Achyranthes.Core drugs:The core drugs for differentiation and treatment of coronary heart disease and angina pectoris are explored through association rules.Under the premise of support of20% and confidence of 0.9,the core drugs of genre differentiation and treatment are Trichosanthes,Scallion White,Qing Pinellia,Bupleurum,Scutellaria,Citrus aurantium,Red Peony,Chuanxiong,Coptis,Tangerine peel,Poria,Peach kernel,Safflower,Salvia,Panax notoginseng powder,Guizhi,Pueraria lobata,Astragalus.Under the premise of support of 30% and confidence of 0.9,the core drugs of the schools for differentiation and treatment of coronary heart disease and angina pectoris with phlegm and blood stasis syndrome are trichosanthes,scallion white,salvia miltiorrhiza,chuanxiong,red peony root,chaihu,citrus aurantium,and kudzu root;Lei Laobian The core drugs for treatment are Danshen,Panax Notoginseng Powder,Trichosanthes,Scallion White,Chuanxiong,Tangerine Peel,Pueraria lobata Root,Ginseng,Ophiopogon,Schisandra,Coptis,Turmeric,Bergamot,and Zedoary;Liu Shi’s core drugs are Danshen,Trichosanthes,Scallion White,Qing Pinellia,Red Peony,Chuanxiong,Peach Kernel,Safflower,Bupleurum,Angelica,Rehmannia,Licorice,Platycodon,Fructus Aurantii,Panax Notoginseng Powder,Ground Dragon,Leech,Cinnamon Twig,Scutellaria,Coptis,Calcined Oyster,Calcined keel;the core medicines of the instructor are Bupleurum,Fructus Aurantii,Fried White Peony,Scutellaria,Qing Pinellia,Poria,Fructus Trichosanthis,Ligusticum Chuanxiong,Salvia Miltiorrhiza.Medication characteristics:The characteristics of genre medications include: emphasis on the theory of "phlegm and blood stasis mutual formation",simultaneous treatment of phlegm and blood circulation;emphasis on the use of qi regulating and invigorating drugs;good use of insects and rattan drugs to treat heart collateral disease;attention to the results of modern drug research;Pay attention to the reasonable compatibility of drugs.The characteristics of Lei Lao’s medication include: the use of experiential prescriptions and the flexibility of adding and subtracting drugs;putting forward a new theory of phlegm and blood stasis,applying equal emphasis on removing phlegm and promoting blood circulation;attaching importance to the multiple effects of drugs and modern pharmacological research;medication neutralization.The characteristics of Liu Shi’s medications include: good at using self-made empirical prescriptions,paying attention to modern pharmacological research;treating phlegm and blood stasis at the same time,resolving blood stasis is more important than resolving phlegm;paying attention to the compatibility application of Qi medicine and blood medicine;Medications for angina pectoris.The characteristics of the instructor’s medication include: good at adding and subtracting prescriptions,the medicine has great effect;paying attention to regulating the cardinal and viscera qi;being good at using rattan drugs to promote blood circulation and collaterals;medication to avoid mutual damage between Yin and Yang and pay attention to the application of anti-adjuvants.Conclusion1."Chang’an Lei’s Heart Disease Phlegm and Blood Stasis School" believes that coronary heart disease angina is a syndrome of deficiency and excess,and corresponding treatment methods are applied by distinguishing different pathological factors.The characteristic is that it can often combine qi deficiency,qi and yin deficiency,toxic heat,and qi stagnation.2.The genre attaches great importance to the theory of "phlegm and blood stasis mutual formation",and uses both phlegm-resolving and blood-activating treatments.Based on this,the Danlou recipe,Danquyin,Guanxinzhuyu Decoction,Xingxiongzhuyu Decoction,etc.have been effective Prescriptions and medicines have precise compatibility and distinctive medicine characteristics.3.Lei Zhongyi,a master of traditional Chinese medicine for more than 60 years,has put forward a new theory of phlegm and blood stasis.Chief Physician Liu Chaofeng is an important inheritor of the school.He pays attention to the treatment of phlegm and blood stasis at the same time when he is taking medicine.The treatment of phlegm and blood stasis is more important than that of phlegm.Chief Physician Zhang Junru inherited the academic thoughts of the development school,while at the same time he had unique insights into the syndrome of stagnation of qi and phlegm,and paid attention to the adjustment of the cardinal and visceral qi machine.4.The academic genre continues to be inherited.On the basis of "phlegm,blood stasis,toxin," and "phlegm,blood,stasis,toxin,and wind," theories have been proposed,many effective prescriptions have been created,and related research is currently underway.In order to provide more treatment methods for coronary heart disease and angina pectoris. |
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