Study On The Correlation Between The Number Of Children With Acute Tonsillitis And Environmental Meteorological Factors In Lanzhou

Objective To investigate the characteristics of children’s acute tonsillitis in Lanzhou area,and to explore the correlation between the number of children’s acute tonsillitis visits per day and environmental meteorological factors.Methods We collected the relevant information of patients diagnosed as acute tonsillitis who visited the second hospital of Lanzhou University and the 940 Hospital of joint logistics support force in Lanzhou from January 1,20l5 to December 31,2017.Collect the environmental data of Lanzhou in the same period(PM_2.5,PM₁₀,CO,SO₂,NO₂,O₃),meteorological data（Temperature（T,℃）,Relative Humidity（RH,%）,Wind speed（W,m/s）and average air Pressure（P,HPa））,and Air quality index（AQI）.Objective to analyze the Spearman correlation and lag effect between environmental meteorological factors and the number of children with acute tonsillitis.The relative risk（RR）was calculated and the exposure-response curve was fitted using the Generalized Additive Models（GAM）in R software.Results （1）The number of pediatric patients with acute tonsillitis in 2015,2016 and2017 was 1481,1488 and 2198,respectively.There was no significant difference between2015 and 2016（P=0.981）,but there was significant difference between 2017 and 2015 and2016（P=0.021,P=0.022）.（2）The number of visits reached a peak in December and a small peak in June.The wave troughs appeared in February and August,and there was no significant difference between the two peaks and the trough.Meanwhile,the number of visits throughout the year showed no obvious seasonal characteristics.（3）Comparison of the number of patients in different age groups showed that the number of patients aged 0-4increased with the increase of age,reached the peak at the age of 4,and then gradually decreased with the increase of age.The trend of male and female children at different ages was the same.（4）In different age groups,the number of male children was higher than that of female children,and there was no significant difference between different genders（P>0.05）.（5）The number of children with acute tonsillar inflammation on a daily basis was positively correlated with AQI,PM_2.5,PM₁₀,CO,SO₂ and NO₂,and negatively correlated with O₃,all of which were significantly correlated.It was negatively correlated with average air temperature and average wind speed（r=-0.060,P=0.048,r=-0.073,P=0.015）,and had no correlation with average air pressure and relative humidity（r=-0.015,P=0.616,R=0.01,P=0.731）.（6）Environmental meteorological factors have a lag effect on the number of daily visits to doctors in children with acute tonsillitis,including single lag effect and cumulative lag effect,and the lag time and lag effect of risk factors are different.Conclusion The number of children with acute tonsillitis in Lanzhou had certain characteristics of time,age and gender.There was a positive correlation between the number of patients and environmental factors in children with acute tonsillitis in Lanzhou area,except for O₃.That is to say,with the increase of air quality index and pollutant concentration,the risk of acute tonsillitis in children increases,and under the same conditions,the risk of acute tonsillitis decreases with the increase of average temperature and average wind speed within a certain range.Each risk factor has a lag effect on the incidence of acute tonsillitis in children.By observing the exposure response curve,we found the change trend of different pollutants and meteorological factors on acute health damage effect of acute tonsillitis.