Patients With Cervical Biopsy HSIL Taper Cutting Postoperative Pathological Upgrade Related Clinnical Analysis Of Influence Factors

Objective Clinical characteristics and associated adjunct examinations were studied in hospitalized patients undergoing cervical conization who had preoperative cervical biopsy results of HSIL,to identify the risk factors for pathological escalation after coning,so as to reduce the colposcopy biopsy in the diagnosis of cervical cancer is insufficient to provide reliable reference,to improve clinical workers by preoperative evaluation of alertness,so that such patients enjoy more effecient diagnosis and treatment services.MethodChoose between January 2018 and December 2020,in the first hospital affiliated to hebei institute of northern hospitalization for HSIL cervical biopsy parallel patients with cervical cold knife cut method of the cone.Finally,494 eligible sample cases were selected.Further study the basic clinical medical records of the patients,such as marriage age,frequency of vaginal delivery,menopause,postcoitalbleeding;Relevant screening data,such as TCT results,high-risk HPV infection and vaginal enviromental status;Relevant examination results,such as the type of cervical transformation zone,lesion invasion points,preoperative biopsy results and postoperative histopathology were recorded.The study on cone cutting postoperative and preoperative biopsy pathology results do self-reflection.Postconing pathology was used as the final standard and divided into the upgraded group and the unupgraded group.The cone cutting postoperative pathological group and not upgrade for the final norm upgrade.The included variables were first tested by univariate chi-square test,and multivariate logistic regression analysis was performed.P < 0.05 was statistically significant.ResultThe study into the cases of 494 cases,cervical cold knife cutting cone postoperative pathological upgrade 38 cases,upgrade rate was 7.7%.Single factor analysis,menopause or not assault points,cervical transformation zone type,lesions invasion points of the cervical cone cutting postoperative pathological upgrade statistically significant(P < 0.01);Marriage age,vaginal delivery times,bleeding after sexual life,TCT results,high-risk HPV infection,vaginal internal environment condition of the cervical cone cutting postoperative pathological upgrade has no statistical significance(P > 0.05).Multiariable Logistic regression equation according to menopause,transformation zone type,taper cutting postoperative pathological lesions assault points to upgrade independent risk factors(OR= 5.633,95% CI 2.153-14.738,P < 0.01;OR=2.657,95%CI 1.025-6.888,P < 0.05;OR=7.552,95%CI 3.221-17.709,P < 0.01).ConclusionThe study results suggest the patient’smenopausal status,cervical transformation zone type,lesion assault points for the cervical cone independent risk factors for postoperative pathological upgrading,for patients with these risk factors,in the course of clinical diagnosis and treatment,the vigilance of preoperative evaluation should be improved,make full evaluation,reduce the misdiagnosis of cervical cancer,in order to provide efficient services for these patients.