| Objective: Excavate ancient and modern Chinese medicine treatment of children anorexia(Syndrome of spleen deficiency and food accumulation)literature,Summarize the rules,and design the recipe for invigorating spleen and eliminating food prescription,and observe its clinical effect to provide a new idea of clinical medication ideas for the treatment of this disease.Methods:1.Literature research:By comprehensively searching and sorting out the ancient and modern literature on the treatment of children anorexia(Syndrome of spleen deficiency and food accumulation),extracting the common prescriptions for the treatment of this disease,Summarize the rule of prescription medication,inductive the frequency and frequency,Using clustering and association analysis to summarize the rules,and combine with clinical experience,designing the prescription for invigorating spleen and eliminating food.2.Clinical research:Adopt the design scheme of self before and after comparison,clinical trials of children who meet the criteria and have complete medical records,the course of treatment was 4 weeks,and the therapeutic effect of TCM syndromes was taken as the main index.Results:1.Literature research: according to the ancient literature analysis,Chinese medicine at baizhu,fuling,orange peel in the top three,respectively,the modern literature paste hawthorn ranked first,followed by fuling,baizhu,thus it can be seen that the ancient and modern physicians treating this disease is value for getting rid of wet and supplement qi,the ancient doctors always supplement qi and spleen medicine for the treatment of this disease,and modern doctors pay more attention to the digestion appetizer spleen,the use of the method of elimination and application of anorexia in children2.Clinical research:A total of 35 cases were selected after invigorating spleen and eliminating food prescription in the treatment of infantile anorexia(type of spleen deficiency and food accumulation),2 weeks of treatment,the effective rate was 40.00%(14);After 4weeks of treatment,the total effective rate was 91.53%(32)and ineffective was 8.47%(3);2 weeks treatment the disappearance rates of main symptoms(poor appetite and reduced food intake)were 11.42%(4)and 8.57%(3),respectively;After 4 weeks of treatment the disappearance rate of main symptoms(poor appetite and reduced food intake)was 48.57%(17)and 37.14%(13),The total scores of TCM symptoms were compared after 2 weeks of treatment and 4 weeks of treatment,The differences were statistically significant(P < 0.01);In the secondary symptoms,93.55%(29)and 70.97%(22)of the minor symptoms did not disappear after 2 and 4 weeks of treatment,This symptom did not improve significantly in most children.The scores of TCM symptoms at baseline were compared with the total scores of TCM symptoms at 2 weeks and 4 weeks of treatment respectively,and the differences were statistically significant(P < 0.01),There were no adverse reactions in this experiment,invigorating spleen and eliminating food prescription has a certain effect on the treatment of anorexia in children(syndrome of spleen deficiency and food accumulation).Conclusion: In ancient books,the treatment of this disease is mainly based on invigorating spleen and replenishing qi,while modern doctors use digesting food and invigorating spleen as the treatment principle.According to the data mining combined with clinical experience,the formula of invigorating spleen and eliminating food is obtained,for which the treatment of children anorexia(spleen deficiency food accumulation syndrome)curative effect is accurate,and safe. |