| Objective:This study took primary dysmenorrhea patients with cold coagulation and blood stasis type as the research object and studied the clinical effect of umbilical refining of heat-sensitive moxibustion of different amounts of moxibustion on treating primary dysmenorrhea of cold coagulation and blood stasis type,providing clinical reference for umbilical refining of heat-sensitive moxibustion on treating primary dysmenorrhea of cold coagulation and blood stasis type.Methods:90 patients who met the inclusion standard were divided into three groups by random number table method,which called the observation group 1(group of sufficient amount of umbilical refining of heat-sensitive moxibustion),the control group(group of heat-sensitive moxibustion on acupoint of CV 8),the observation group 2(group of half an hour amount of umbilical refining of heat-sensitive moxibustion),and 30 cases in each group.Observation group 1 was operated according to the operation method of umbilical refining of heat-sensitive moxibustion,on the basis of appearing the moxibustion feeling of steaming all over the body,slight sweating and relaxation as the standard of sufficient moxibustion.Sufficient amount of moxibustion usually needs more than one hour.Observation group 2 is also operated according to the operation method of umbilical refining of heat-sensitive moxibustion for half an hour moxibustion amount.The control group used heat-sensitive moxibustion on the acupoint of CV 8 and was on the basic of giving manipulation release and putting Chinese medicine powder pill in umbilicus,and the treatment of heat-sensitive moxibustion was one time until the feeling of heat-sensitive moxibustion disappeared.The treatment of moxibustion was applied to all the three groups 7 days before menstruation,once a day for consecutive 7 days.It lasted for a total of 3 menstrual cycles.After treatment,until the end of the menstruation of patients,Cox Menstrual Symptom Scale,Visual Analogue Scale and traditional Chinese medicine dysmenorrhea syndrome score(TCM syndrome score)were used to evaluate the differences of curative effect before and after treatment.The patients had a follow-up of 3 months after the treatment and the long-term effect was evaluated.Results:1.In this study,89 patients completed treatment totally,among them,1 patient in the observation group 2 was observed to voluntarily withdrew from the study due to personal reason.There was no statistical difference in aspects of age,course of disease,pain degree,symptoms and syndromes scores of patients in each group before treatment(P>0.05),which showed comparability.2.The result of pain severity comparison:VAS scores and their differences in each group did not meet normal distribution,so,M(P25,P75)was used to represent VAS scores and their differences.The difference of VAS scores was significantly improved in each group before and after treatment(P<0.01).After treatment,there was no difference between 5.00(4.00,6.125)in the observation group 1 and 5.50(4.00,6.625)in the control group(P>0.05),the difference between the two groups was greater than 3.00(2.00,3.00)in the observation group 2,the difference was statistically(P<0.05).Between the before treatment and follow-up,all the three groups had statistical significance in VAS scores(P<0.05).At the follow-up time,the score difference of the observation group 1 was 5.00(5.00,7.00),which was higher than 3.50(3.00,5.00)of the control group and 1.00(0.00,1.00)of the observation group 2,respectively,and the score difference of the control group was obviously higher than the observation group 2,each group had significant differences in comparison(P<0.01).3.The result of the Cox dysmenorrhea symptom score comparison:The difference of symptoms scores in each group was significantly improved before and after treatment(P<0.01).After treatment,there was no difference between(16.83±6.52)of the observation group 1 and(15.43±7.96)of the control group(P>0.05),and the difference between the two groups was significantly higher than that in the observation group 2(10.34±6.62)(P<0.01).At the follow-up time,the score difference of the observation group 1 was(15.60±6.80),which was higher than(11.93±5.01)of the control group and(7.76±5.63)of the observation group2,respectively,each group had differences in comparison(P<0.05),the score difference of the control group was obviously higher than the observation group2(P<0.01).4.The result of TCM syndrome score comparison:The difference of TCM syndrome scores in each group was significantly improved before and after treatment(P<0.01).After treatment,there was no difference between(13.23±6.05)of the observation group 1 and(12.70±3.82)of the control group(P>0.05),and the difference between the two groups was significantly higher than that in the observation group2(9.45±4.99)(P<0.01).At the follow-up time,the score difference of the observation group 1 was(12.10±6.08),which was higher than(9.47±4.69)of the control group and(4.33±3.99)of the observation group 2,respectively,each group had differences in comparison(P<0.05),the score difference of the control group was obviously higher than the observation group 2(P<0.01).5.Comparison of curative effect after treatment:Therapeutic effect of TCM syndromes and Cox dysmenorrhea symptoms in each group were different statistically(P<0.05).The cure and marked curative effective rate of syndromes and symptoms in observation group 1 was 76.67%,the cure and marked curative effective rate of syndromes and symptoms in the control group was 73.33%,the cure and marked curative effective rate of symptoms in observation group 2 was 41.38%,and the cure and marked curative effective rate of syndromes in observation group 2 was43.33%.There was no statistical difference on therapeutic effect of TCM syndromes and Cox dysmenorrhea symptoms between the observation group 1 and the control group(P>0.05),and the curative effect of syndromes and symptoms in the two groups were higher than those in the observation group 2,the differences were statistically significant(P<0.05).6.Comparison of curative effect after a follow-up:Therapeutic effect of TCM syndromes and Cox dysmenorrhea symptoms in each group were different statistically(P<0.05).The cure and marked curative effective rate of syndromes and symptoms in observation group 1 was 76.67%,the cure and marked curative effective rate of syndromes and symptoms in the control group was 73.33%,the cure and marked curative effective rate of symptoms in observation group 2 was 41.38%,and the cure and marked curative effective rate of syndromes in observation group 2 was43.33%.There were statistically significant differences in the curative effect of syndromes and symptoms between the observation group 1 and the control group(P<0.05).The therapeutic effect of TCM syndromes and Cox dysmenorrhea symptoms of the observation group 1 was higher than the observation group 2 and the control group,and the control group was higher than observation group 2,the differences were statistically significant(P<0.05).Conclusion:1.Umbilical refining of heat-sensitive moxibustion can effectively ameliorate the main symptoms and the TCM syndrome of primary dysmenorrhea of cold coagulation and blood stasis type,and the long-term curative effect is stable.2.In order to meet the requirement of sufficient amount of moxibustion,the sufficient amount of moxibustion is the key to achieve the best clinical efficacy in the operation of umbilical refining of heat-sensitive moxibustion. |