Influencing Factor Analysis Of Postoperative Intracranial Infection Related To Frontal Sinus Opening During Operation

Objective:To explore the correlation factors between different management methods of intraoperative frontal sinus opening and postoperative intracranial infection.Methods:A retrospective analysis was performed on 159 patients with intraoperative frontal sinus opening in the First Hospital of Shanxi Medical University from January1,2007 to December 31,2019.The relevant data were consulted,and the frontal sinus treatment was counted.Meanwhile,the days of preventive antibiotic use,drainage tube placement and postoperative intracranial infection were recorded.Univariate and multivariate Logistic regression were used to analyze the correlation between different treatment methods of frontal sinus opening and intracranial infection.Results:A total of 159 patients with intraoperative frontal sinus opening were included in this study,including 34 patients with postoperative intracranial infection,with an incidence of 21.4%.Single factor analysis results showed that age,frontal sinus mucosa is rejecting,electric bright frontal sinus wall,frontal sinus wall bone grinding,pedicle periosteal flap coverage,antibiotics to prevent the use of more than48 h and intracranial infection was not statistically significant(P>0.05),gender,cut epidural frontal sinus treatment,frontal sinus open area,the operation time,drainage tube placement and the number of days and intracranial infection occurred statistically significant(P<0.05);Further Logistic stepwise regression analysis showed that gender,open dural frontal sinus closure,pedicled periosteum flap coverage,operation duration over 7h,frontal sinus open area,drainage tube placement over 1d,and postoperative intracranial infection were correlated to a certain extent.Conclusion:In male patients,surgical duration exceeding 7h,large frontal sinus open area,and days of drainage tube placement exceeding 1d will increase the risk of postoperative intracranial infection,while careful treatment of the frontal sinus and closure of the frontal sinus before dural incision and covering the frontal sinus with pedicled periosteum flap will reduce the incidence of intracranial infection.