| Background: Primary liver cancer(PLC)is one of the most common gastrointestinal malignancies in the world,currently ranking the 7th in the world,the4 th in China,and the 2nd in the cause of cancer death [1].It is a serious threat to people’s life and health,and the main cause of its occurrence in China is still viral hepatitis B [1].Although with the standard application of hepatitis vaccine and the improvement of people’s awareness of the disease,the incidence and mortality of PLC in China are declining,but because of the vast population base and the improvement of the proportion of people willing to take the initiative in health examination,there are still a large number of new liver cancer patients every year.Small hepatocellular carcinoma(SHCC),as one of the primary hepatocellular carcinoma,has a relatively good prognosis due to its unique biological characteristics.Currently,researches on it are becoming more and more perfect,including hepatic resection(HR),liver transplantation(LT),microwave ablation(Microwave ablation),etc.Currently,MWA or Radio Frequency Ablation(RFA),transarterial chemoembolization(TACE),and drug therapy are the main treatment methods for small liver cancer.Each method has its own advantages and disadvantages as well as indications.In the process of clinical practice,how to choose each method and treat patients according to this method has become a topic of increasing concern to hepatobiliary surgeons.Objective: In this study,the safety and effectiveness of laparoscopic ultrasound-guided liver microwave ablation and laparoscopic hepatectomy in the treatment of small liver cancer were compared,and their advantages and disadvantages were clarified,so as to provide a basis for clinicians to make the choice of surgical plan in the case of small liver cancer.Methods: In this study,Choose patients during June 2016 to June 2019 in Xiangyang NO.1 People’s Hospital of laparoscopic ultrasound-guided microwave ablation of liver cancer or treated with laparoscopic liver resection of the clinical data of28 patients with small liver cancer were retrospectively analyzed,according to major surgery,it can be divided into two groups,including laparoscopic ultrasound-guided microwave ablation of liver cancer as the observation group,a total of 15 cases,laparoscopic liver resection as the control group,a total of 13 cases.Intraoperative data and postoperative data were compared between the two groups.Intraoperative data included: operative time,intraoperative blood loss;Postoperative data including:postoperative alanine aminotransferase(ALT),aspartate aminotransferase(AST),total bilirubin(TBil),albumin(propagated)index,incidence of postoperative complications after awake anesthesia,pain score(digital scoring method),postoperative hospital stay,postoperative abdominal enhanced CT and DSA imaging results at 1 month,1 month after liver cancer patients quality of life measurement scale score and postoperative 1year disease-free survival differences.Results: Compared with the control group,the observation group had less intraoperative bleeding,shorter operative time,shorter postoperative hospital stay,and smaller pain score after anesthesia.There were no significant differences in ALT,AST,TBIL,ALB and effective rate between the two groups at 1,3,5 days after operation,1month after operation,quality of life scale score of liver cancer patients at 1 month after operation,incidence of postoperative complications,and 1-year postoperative tumor-free survival rate.Conclusion: Laparoscopic ultrasound-guided microwave ablation of liver cancer is comparable to laparoscopic hepatectomy in terms of safety and effectiveness,while laparoscopic ultrasound-guided microwave ablation of liver cancer has less trauma and is conducive to faster recovery of patients. |
PDF Full Text Request