COMSOL Simulation Of Photoacoustic Imaging Of Breast Tissue And The Related Tumor

Breast cancer is considered to be one of the most malignant tumors among women all the world and become the main cause of cancer-related deaths in women.Early detection of breast cancer has become the most effective measure to reduce the mortality of breast cancer.Photoacoustic imaging not only has the advantages of high contrast of optical imaging and strong penetration of acoustic imaging,but also become an imaging method with the advantages of non-invasive,non-radioactive and clinically easy to operate.Photoacoustic imaging can overcome some limitations in clinical diagnosis of cancer,which has unlimited potential in the early diagnosis of breast disease.In this thesis,the finite element analysis software COMSOL Multiphysics is used to build an optical model of breast tissue.Photoacoustic signals generated using the thermal expansion of tumor volume elements during photoacoustic imaging are successfully obtained by coupling and calculating of multiple physical fields,including coefficient partial differential equations,bio-thermal equations,solid mechanics and pressure acoustics.In addition,The differences of some important physical quantities in the simulation process under different parameters and their causes were analyzed.The results show that the finite element model of breast tissue and the related tumor established in this paper is effective,which not only enables researchers to theoretically simulate the whole process of photoacoustic imaging,but also provides a new way of thinking for the study of photoacoustic imaging in the detection and imaging of early breast tumor.