| Objective: To investigate the application value and significance of DPOAE and ABR in patients with unilateral primary tinnitus with normal hearing threshold.METHODS: Thirty-five patients with unilateral primary tinnitus with normal hearing threshold(the affected ear was on the tinnitus side,and the opposite ear was on the non-tinnitus side)who were treated in the outpatient department of our hospital from October 2019 to October 2020 were collected.The tinnitus volume matching,Tinnitus handicap inventory filled out,DPOAE and ABR tests were performed,and the results of each test were statistically analyzed.Results:(1)The tinnitus loudness of all patients could be successfully matched.there are 27 patients with tinnitus volume being no more than 10 d B,6 patients with tinnitus volume being 11-20 d B and 2 patients with tinnitus volume being >20 d B;in the tinnitus handicap inventory,2 patients are of Level 1,5 patients are of Level 2,13 patients are of Level 3,14 patients are of Level 4,and 1 patient is of Level5.Spearman rank correlation test showed that there was no statistical significance between tinnitus loudness and tinnitus severity(P > 0.05).(2)The DPOAE noise ratio positive rates of the deaf ear subject to 0.75 k HZ,1.0k HZ,1.5k HZ,2.0k HZ,3.0k HZ,4.0k HZ,6.0k HZ and 8.0k HZ are 85.71%,85.71%,82.86%,68.57%,71.43%,68.57%,74.29% and 68.57%;The DPOAE SNR positive rates of the opposite ear are 100.00%,100.00%,100.00%,97.14%,100.00%,97.14%,100.00% and 100.00%;The DPOAE amplitude positive rates of the deaf ear are71.43%,68.57%,62.86%,42.86%,42.86%,40.00%,45.71% and 42.86%,respectively.The DPOAE amplitude positive rates of the opposite ear are 100.00%,100.00%,94.29%,94.29%,91.43%,91.43%,94.29% and 88.57%;According to the relevant data analysis,the difference in DPOAE SNR positive rate of the deaf ear and the opposite ear subject to 1.5k HZ,2.0k HZ,3.0k HZ,4.0k HZ,6.0k HZ and 8.0k HZ is of statistical significance(P<0.05),but the difference in DPOAE SNR positive rate of the deaf ear and the opposite ear subject to 0.75 k HZ and 1.0k HZ has no statistical significance(P>0.05).The difference in DPOAE amplitude of the deaf ear and the opposite ear subject to 0.75 k HZ-8.0k HZ is of statistical significance;The difference in DPOAE amplitude and SNR positive rate of the deaf ear subject to 2.0k HZ,3.0k HZ,4.0k HZ,6.0k HZ and 8.0k HZ is of statistical significance(P<0.05),but the difference in DPOAE amplitude and SNR positive rate of the deaf ear subject to0.75 k HZ,1k HZ and 1.5k HZ has no statistical significance(P>0.05).The DPOAE amplitude and SNR of the opposite ear subject to all frequencies have no statistical significance(P>0.05).(3)The latency of ABR I wave was prolonged in 13 cases,the latency of ABR III wave was prolonged in 6 cases,and the latency of ABR V wave was prolonged in 3cases.The values of I-III,III-V and I-V wave interval were normal.Only I and V wave latency were compared with contralateral ear,and the difference was statistically significant(P <0.05).There was no significant difference in I-III,III-V and I-V wave intervals between affected ear and contralateral ear(P >0.05).Conclusion:(1)In unilateral primary tinnitus with normal pure tone hearing threshold,tinnitus loudness has no significant correlation with tinnitus severity.(2)Normal pure tone audiometry does not mean normal function of the auditory system.DPOAE can detect early cochlear lesions before pure tone audiometry,and its amplitude may be more sensitive than the signal-to-noise ratio.(3)For patients with unilateral primary tinnitus,DPOAE and ABR should be combined to detect the potential lesions of the auditory system in a more comprehensive and more effective way,which is of great clinical significance for guiding clinical diagnosis and treatment. |
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