The Current Status And Correlation Between Self Perceived-burden And Quality Life Among Patients With Non-hodgkin’s Lymphoma

Objective: To evaluate the current status of self-perceived burden and its impact factors among patients with Non-hodgkin’s lymphoma(NHL);To identify the relevant factors that affect self-perceived burden in patients with non-hodgkin’s lymphoma;To determine the correlation between self-perceived burden and quality of life in patients with non-hodgkin’s lymphoma.Methods: A total of 169 patients with non-hodgkin’s lymphoma and their primary caregivers who were hospitalized in ruijin hospital affiliated to a three grade hospital in Shanghai from January to October 2019 were enrolled by convenient sampling method.Self-designed general information questionnaire,social support rating scale(SSRS),Self-rating depression scale(SDS),Self-perceived burden scale(SPB)and Function-assessment of cancer therapy-Lymphoma(FACT-Lym)scale were used.Statistical analysis methods include:(1)Statistical description: descriptive statistics are made by means of mean,standard deviation and constituent ratio;(2)Multivariate analysis was used to explore the influence factors of self-perceived burden and quality of life in patients with non-hodgkin’s lymphoma.(3)Pearson or Spearman analysis was used to explore the correlation between self-perceived burden,social support,self-assessment of depression and quality of life in patients with non-hodgkin’s lymphomaResults:(1)In this study,170 questionnaires were distributed and 169 were recovered,with the effective recovery rate of 99.41%.The average age of the patients was 50.14±14.63 years old.The score of self-perceived burden of non-hodgkin’s lymphoma patients was(28.95±11.27),and the average score of economic dimension was(3.13±1.37),the average score of emotional dimension was(3.01±1.20),the average score of physical dimension was(2.76±1.13).There were 78.88% of patients with self-perceived burden,and 55.56% of patients with moderate to severe elf-perceived burden.(2)The results of stratified regression analysis showed that the factors influenced by patients with caregiver burden(β=0.346,P<0.01),low the family income per month(β=-0.229,P<0.01),depression(β=0.213,P<0.01),status of replase(β=0.197,P<0.05),and of non-hodgkin’s lymphoma patients’ self-perceived burden and those explained the variation of33.6% of the total variance.(3)The quality of life score of non-hodgkin’s lymphoma patients was 115.63±26.25,which was in the middle level.The highest mean score in the social and family dimension was3.42±0.86,the physiological status dimension was 2.82±0.81,the lymphoma specific items were 2.80±0.73,the emotional status dimension was 2.48±0.67 and the lowest mean score in the functional status dimension was 2.29±0.95.(4)The results of stratified regression analysis showed that the factors influenced by patients with depression(β=-0.374,P<0.01),physical condition(β=-0.341,P<0.05),self perceived burden(β=-0.200,P<0.01),and the level of social support(β=0.163,P<0.01)of non-hodgkin’s lymphoma patients’ quality of life and those explained the variation of 53.00%of the total variance.Conclusion:(1)The self-perceived burden of non-hodgkin’s lymphoma patients was at a mild level,in which the economic dimension scored the highest,and the economic burden of the patients was heavier.(2)Families with low per capita monthly income,relapsed patients,depression,caregivers with heavy burden of patients self-feeling burden,medical staff should focus on.(3)The quality of life of patients with non-hodgkin’s lymphoma was at a medium level,with the highest score in the social and family dimension and the lowest score in the functional status dimension.(4)Non-hodgkin’s lymphoma patients with symptoms of depression,inability to take care of themselves,high levels of self perceived burden and low levels of social support have poor quality of life and should be concerned by healthcare professionals.(5)There is a negative correlation between the self-perceived burden of non-hodgkin’s lymphoma patients and the quality of life of patients,so for patients with a heavy self-perceived burden,medical personnel should identify and intervene early to improve the quality of life of patients.