Objective: Through the observation of nourishing liver and kidney decoction combined to bend Progesterone tablets The clinical curative effect of treatment of liver and kidney Yin deficiency type meno Pausal transition abnormal uterine bleeding(AUB)may be required,Compared with Pure use to bend Progesterone,hemostatic efficacy,TCM symptoms was observed,sex hormone levels,anemia,improve the situation,Endometrial thickness and the recurrence rate level,the objective to evaluate the effect of nourishing liver and kidney soup,for the idea and method for the treatment of the disease to Provide more.Methods: From September 2019 to September 2020 collected in the gansu Province hospital infertility clinic,in-Patient department of obstetrics and gynecology,discharge standard of 60 Patients with liver and kidney Yin deficiency type AUB menopausal transition,Were randomly divided into treatment group(n = 30)and control group(n = 30).Just use to bend Progesterone tablets as control group: two groups of Patients were diagnosed as curettage Postoperative Pathological returns for endometrial simple living,Control shall be 15 days after oral Progesterone to bend,10 mg/tablet,twice daily,even served 10 days,the next cycle starting from 15 th day menstruation,a total of three cycles.On the basis of the control group and treatment group with soup of nourishing liver and kidney,Postoperative day 5 oral soup of nourishing liver and kidney,(Fructus Ligustani 18 g,Moxanlian 18 g,Shengdi 15 g,Digu Pii15 g,Baishao 15 g,Ejiao12g,Xuanshen 10 g,Diduan 10 g,Maidong 10 g,Cuscuta 15 g,Rubiao12g,Xianhe 15g)and Glycyrrhizae 10g),If the vaginal bleeding stopped,Rubiao 12 g and Xianhe 15 g were removed,and Dangshen 12 g and Atractylodes Atractylodes 10 g were added.A daily dose,morning and evening Points to take,menstrual non-sto P medicine;Progesterone tablets to bend them with the control group only,a total of treatment of three menstrual cycles.Result:1.The hemostatic efficacy: through statistical test analysis,simple to use flexor Progesterone Patches of the control grou P total effective rate was 82.7%,and with nourishing liver and kidney decoction treatment group total effective rate was 93%,Research results show that the two groups in the treatment of vaginal bleeding stop time and there is no obvious difference of curative effect(P > 0.05).2.Syndromes curative effect: after statistical analysis,from the Point of the overall improvement of syndromes,control group total effectiveness 82.80%,treatment group was93.10%,The comparison group,two groups of symptoms were improved,comparison between groups,Treatment group in improving the syndrome is better than that in control group,the difference was statistically significant(P < 0.05).3.The TCM syndrome integral,the statistical test,comparison between groups,two groups of Patients before treatment in TCM syndrome integral is no statistical difference(P >0.05),two groups of comparable,The intra-group comparison showed that there was statistical significance between the two groups before and after treatment(P<0.05),suggesting that both treatment methods could reduce the TCM syndrome scores of Patients.There was significant difference between the two groups(P < 0.05),the treatment group was better than the control group that of control group in lower TCM syndrome score.4.Individual symptoms of traditional Chinese medicine: through statistical tests,Prompted two groups of comparable;Comparison between before and after treatment group,Two groups have statistical significance on the single symptom improvement of traditional Chinese medicine(P < 0.05);But the treatment group in improving the menstrual cycle,the bleeding,menstrual Period,lumbar debility,dry mouth,dry throat,two zygomatic flush,five upset hot,night sweats,stool stem node is better than that in control group,And statistically significant difference(P < 0.05);To improve menstrual color,dizziness,tinnitus,insomnia,much dream no statistical differences(P > 0.05),Conclusion: the two groups can improve the individual symptoms of traditional Chinese medicine,but the treatment group in improving the menstrual cycle,the bleeding,menstrual Period,lumbar debility,dry mouth Pharynx dry,two zygomatic flush,five upset hot,night sweats,stool stem node is better than that in control group,In the improvement of menstrual color,dizziness tinnitus,insomnia and many dreams.5.The hemoglobin(Hb): the statistical test,comparison between groups before treatment,two groups of Hb content no statistical difference(P > 0.05),Prompted comparable between the two groups,Within group after treatment,two groups of treatment can increase Hb,statistically significant difference(P < 0.05);Com Parison between grou Ps after treatment,Compare of Hb two groups have significant difference(P < 0.05),the results suggest: two treatments could increase Hb,but the treatment group curative effect is better than the control group.6.Serum FSH,LH and E2: Statistical analysis dis Play FSH,LH,E2 differences between the two groups has no statistical significance before treatment(P > 0.05),indicating comparability,In the two groups after treatment can reduce FSH,but there is no statistical difference of in reducing the effect of FSH levels(P > 0.05);Control the impact on the level of LH,E2 level had no significant change(P > 0.05),the treatment group can be lower levels of LH,E2 levels increased,statistically significant difference(P < 0.05);Results treatment group in improving the organic LH,E2 level is better than that in control group.7.Vaginal ultrasound endometrial thickness: through statistical tests,the two groups in the treatment of endometrial thickness is no statistical differences(P > 0.05),Prompted two groups of comparable,Within group after treatment,all can make reduce the lining thickness,similar between the two groups have statistical significance(P < 0.05),after treatment comparison between groups,two groups have significant difference(P < 0.05);Results suggest two groups all can reduce the endometrial thickness,the treatment group effect better.Results suggest add a soup of nourishing liver and kidney of the recurrence rate is lower.8.The comparison of relapse rate: through statistical tests,treatment after 3 cycles,the control group recurrence rate was 34.5%,the treatment group recurrence rate was 10.3%,the comparison between the two groups was statistically significant(P < 0.05);The results indicated that the recurrence rate of adding Ziguanshen decoction was lower.Conclusion:In the treatment of Perimenopausal abnormal uterus with deficiency of liver and kidney Yin,the clinical efficacy of Ziguangshen Decoction combined with ddrogesterone tablet is better than that of ddrogesterone alone,and it has good clinical efficacy in improving traditional Chinese medicine syndromes in perimenopausal Period,correcting anemia,regulating hormone levels,reducing endometrial thickness and other aspects,Low recurrence rate,less adverse reactions,worthy of clinical Promotion. |