To Explore The Related Risk Factors Of Acute Myocardial Infarction In Patients With Acute Ventricular Aneurysm

Objective: To explore the risk factors and clinical characteristics of acute myocardial infarction in patients with acute ventricular aneurysm.Method: A single-center retrospective study method is used to collect 2154 patients with acute myocardial infarction who were hospitaled in the Department of Cardiology of the Second Hospital of Tianjin Medical University from June 2016 to June 2019,among them there are 1058 patients have completed informations,according to the result of Echocardiography,55 patients were diagnosed as ventricular aneurysm,divided into ventricular aneurysm group,225 patients are selected as non-ventricular aneurysm group.Clinical and biochemical informations are collected for all patients.Measurement data use mean±standard deviation(x±s),or interquartile range M(P25,P75),and t-test or nonparametric rank sum test is used for single factor analysis;Count data use frequency and ratio(n %),chi-square test is used for single factor analysis.Then choosing meaningful factors into binary logistic regression model,explore the independent risk factors.Result:1.1The baseline data: Between the two groups in age,chest pain time,hypertension age,whether hypertension control is effective,diabetes,arrhythmia,myocardial infarction,angina attack,drinking age and grams differences significantly(p < 0.05).However,there are not significantly difference in gender,cerebral infarction,pulmonary disease,smoking and its number of years,family history(p >0.05).1.2Laboratory biochemical indicators: there are significantly differences in the levels of transaminase,creatinine and NT-proBNP(p < 0.05);There are not significantly difference in LDL,FBG and troponin(p >0.05).1.3Other relevant clinical examination indicators: there are significantly differences in cardiac function grade at admission and ejection fraction,different sites of myocardial infarction,diseased vascular sites,and the magnitude of ECG changes(p < 0.05).There are not significantly difference in number of diseased vessels,doing PCI(p >0.05).1.4Multivariate Logistic regression analysis: There are statistical differences in whether hypertension control meets the standards,chest pain time,and ejection fraction.Inadequate hypertension control and long chest pain time can be used as independent risk factors for the occurrence of acute ventricular aneurysm after myocardial infarction.The ejection fraction is closely related to the occurrence of acute ventricular aneurysm.Conclusions :(1)Ineffective hypertension control and long chest pain time have independent predictive value for the occurrence of acute myocardial infarction with acute ventricular aneurysm.(2)High NT-proBNP levels,increasing age,long chest pain time,ineffective hypertension control,diseased vascular sites,different sites of myocardial infarction and ECG changes are risk factors for acute ventricular aneurysm.(3)Previous angina pectoris is a protective factor for ventricular aneurysm.