Comparison Of Clinical Value Between Fluorescent Laparoscopy And Ordinary Laparoscopy In Radical Resection Of Colorectal Cancer

Objectives:To explore the difference of clinical efficacy between fluorescent laparoscopy and ordinary laparoscopy in radical resection of colorectal cancer,and to illustrate the applicability of fluorescent laparoscopy in clinical treatment of colorectal cancer.Methods:According to the inclusion criteria and exclusion criteria,colorectal cancer patients admitted to the Second Unit of Gastrointestinal Surgery Department of the Second Affiliated Hospital of Kunming Medical University from July 2019 to January 2021 were collected and divided into two groups:ordinary laparoscopic colorectal cancer radical treatment group and fluorescent laparoscopic colorectal cancer radical treatment group.Patients in the two groups were matched in terms of gender,age,body mass index,tumor location,etc.A total of 60 cases were collected for study,including 40 cases in the ordinary laparoscopic group and 20 cases in the fluorescent laparoscopic group.Contrastive analysis was made on the postoperative tumor conditions of the two groups:tissue differentiation,T grade,N grade,vascular tumor embolism and nerve invasion;Surgain-related indicators:operative time,operative blood loss,number of lymph nodes dissected,number of metastatic lymph nodes,first postoperative exhaust time,detection of lymph nodes in 253 groups of rectal cancer,postoperative short-term complications,length of stay after surgery,total hospitalization cost and other indicators.Results:1.There was no statistical significance in the degree of tissue differentiation,T grade,N grade,vascular invasion or nerve invasion between the ordinary laparoscopic group and the fluorescent laparoscopic group(P>0.05).2.There were no significant differences in operative time,intraoperative blood loss,the number of metastatic lymph nodes and the first postoperative exhaust time between the two groups(P>0.05).The total number of lymph nodes removed in the ICG group was significantly higher than that in the ordinary laparoscopic group(18 vs 13),with statistically significant difference(P=0.009).3.In patients with rectal cancer,the number of lymph nodes detected in the ICG group 253 was more than that in the ordinary laparoscopic group,and the difference was statistically significant(P<0.05).4.Both groups of patients had different degrees of postoperative short-term complications,the fluorescence abdominal cavity group with 3 postoperative complications were lower than the ordinary laparoscopic group(20.00%and 37.50%),but there was no statistical significance(P>0.05).5.There was no statistical significance in medical insurance category,i.e.payment method,between the two groups(P>0.05),but the postoperative hospital stay and overall cost during hospitalization in the fluorescence laparoscopy group were lower than those in the ordinary laparoscopy group,with statistical differences(P<0.05).Conclusions:1.Fluorescence laparoscopy based on indoxyanine green can identify relevant lymphatic drainage and anastomotic vascular perfusion in real time during radical resection of colorectal cancer,which has a good clinical application prospect.2.Fluorescence laparoscopy can help surgeons to increase the number of dissected lymph nodes on the premise of ensuring the successful completion of surgery,so as to achieve the purpose of radical treatment,and play a positive guiding role in the evaluation of postoperative pathological staging and postoperative treatment of colorectal cancer patients.3.Indocine green is easy to use,and fluorescence laparoscopy does not increase the learning time of surgeons,which is worthy of further study and application in clinical practice.