Clinical Study Of Chaihu Plus Longgu Muli Decoction In The Treatment Of Phlegm Heat Type Hypertension With Insomnia

Objective: To explore the efficacy and safety of Chaihu plus Longgu muli Decoction in the treatment of phlegm heat type hypertension combined with insomnia,enrich the theory of Shaoyang as pivot,and provide new ideas and methods for guiding the curative effect.Methods: 82 cases of clinical observation were randomly divided into the control group and the experimental group.The control group was given conventional western medicine treatment,and the experimental group was given Chaihu plus Longgu muli Decoction on the basis of the conventional western medicine treatment.The treatment cycle was 4 weeks.The blood pressure level,24-hour ambulatory blood pressure,Pittsburgh sleep quality index(PSQI),TCM syndrome score,safety and adverse reactions of the two groups before and after treatment were observed and statistically analyzed.Results: 1.Comparison of blood pressure curative effect: After treatment,the blood pressure level in the office of the two groups of patients was lower than before treatment,and the difference was statistically significant(P<0.05).The decrease in the experimental group was more significant than that of the control group(P<0.05).Comparison of 24-hour dynamic blood pressure showed that after treatment,the daytime mean systolic blood pressure(d SBP),daytime mean diastolic blood pressure(d DBP),nighttime mean systolic blood pressure(n SBP),nighttime mean diastolic blood pressure(n DBP),24-hour mean systolic blood pressure(24h SBP)and 24-hour mean diastolic blood pressure(24h DBP)in the two groups decreased compared with before treatment,with statistical significance(P <0.05).Compared with the control group,except diastolic blood pressure at night,the dynamic blood pressure at 24 hours after treatment in the test group was significantly lower than that in the control group(P < 0.05).2.Insomnia improvement: After treatment,the PSQI score of the test group dropped from 13.90 to 7.10,and the control group dropped from 13.08 to 9.30.Comparison between the groups,the PSQI score of the test group was significantly lower than that of the control group after treatment(P<0.05).3.Improvement of TCM symptoms: After treatment,the scores of TCM syndromes in the two groups were lower than those before treatment.The scores of TCM syndromes in the test group were significantly lower than those in the control group(P<0.01);compared with the control group,the TCM syndrome scores in the test group after treatment The individual symptom scores were all less than 0.05,and the difference was statistically significant.4.Safety and adverse reactions: During this treatment,no adverse reactions occurred in the two groups of patients.After treatment,the patients had no obvious abnormalities in blood routine,second stool routine,liver and kidney function and other indicators.Conclusion: Chaihu plus Longgu muli Decoction combined with conventional western medicine treatment is more conducive to alleviating the clinical symptoms of patients with phlegm-heat internal disturbance hypertension and insomnia,improving the blood pressure level of the patients,and improving the sleep quality of the patients,and the medication is safe,and the adverse reactions are low.