| Objective:To evaluate the clinical efficacy of regulating the liver,nourishing kidney and removing blood stasis method in the treatment of diabetes with insomnia by Meta-analysis,so as to provide a feasible method for the clinical treatment of diabetes with insomnia.Methods:CNKI,Wanfang Data,VIP and MEDLINE were searched by computer.The randomized controlled trials(RCT)of regulating the liver,nourishing kidney and removing blood stasis in the treatment of diabetes with insomnia from 1990 to June 2020 were searched.After extracting the total effective rate of sleep,PSQI,TCM syndrome score,blood glucose(FBG、2hPG and HbAlc),Revman 5.4 software was used to analyze the data.Objective to analyze the typical cases of diabetes with insomnia treated by the method of regulating the liver,nourishing kidney and removing blood stasis,and further prove the effectiveness of this method.Result:1.A total of 12 articles were included,including 968 patients with diabetes and insomnia.The results of Meta-analysis showed that:(1)The use of traditional Chinese medicine(or combined with western medicine)to regulate the liver,nourish the kidney,and remove blood stasis in the treatment of diabetes with insomnia is better than the use of western medicine alone in terms of sleep clinical efficacy[Z=5.22(P<0.00001)].(2)The improvement in PSQI scores of patients with diabetes and insomnia treated with traditional Chinese medicine(or combined with western medicine)for regulating liver,nourishing kidney and removing blood stasis was better than that of western medicine alone[Z=4.15(P<0.00001)].(3)The use of traditional Chinese medicine(or combined with western medicine)to regulate the liver,nourish the kidney and remove blood stasis in the treatment of diabetes with insomnia was better than the use of western medicine alone in the improvement of TCM syndrome[Z=8.72(P<0.00001)].(4)The improvement of blood glucose in the treatment of diabetes accompanied by insomnia with traditional Chinese medicine(or combined with western medicine)for regulating liver,nourishing kidney and removing blood stasis is better than that with western medicine alone.2.Through typical cases,it is proved that the traditional Chinese medicine of regulating the liver,nourishing kidney and removing blood stasis can improve the sleep and blood glucose of patients with diabetes and insomnia.Conclusion:Diabetes and insomnia patients were treated with regulating the liver,nourishing kidney and removing blood stasis method of TCM,which had good curative effect in adjusting sleep,improving PSQI score and TCM syndrome and reducing blood glucose. |