The Research Of Correlation Between Sublingual Vein And The Degree Of Coronary Artery Stenosis In Middle-aged Patients With Thoracic Obstruction

ObjectiveTo analyze the correlation between the sublingual vein signs and the degree of coronary artery stenosis in middle aged patients with thoracic obstruction,and to explore the predictive value of the sublingual vein signs for coronary heart disease in middle aged patients with thoracic obstruction,to provide more sufficient clinical objective basis for the early prevention and treatment of middle-aged coronary heart disease.MethodsAccording to the inclusion criteria,a total of 182 middle-aged patients with thoracic obstruction admitted to the Department of Cardiology of Guangdong Integrated Traditional Chinese and Western Medicine Hospital and Foshan Hospital of Traditional Chinese Medicine from January 2020 to January 2021 were collected.Suburlingual vein was evaluated within 48 hours after admission by dooctors.Coronary angiography or coronary CTA examination were performed during hospitalization.According to the examination results,82 patients were divided into CHD group and 88 patients were divided into non-CHD group.General information for CHD were collected for all patients,including age,sex,elevation,weight,history of hypertension,history of diabetes,triglyceride(TG),total cholesterol(TC),low density lipoprotein cholesterol(LHDL-C),high density lipoprotein cholesterol(HDL-C),blood uric acid(UA)levels.SPSS 22.0 was used to conduct statistics on the obtained data:To analyze the baseline data of the CHD group and the non-CHD group;To compare and analyze sublingual vein scores of CHD group and non-CHD group;To analyze the relationship between the degree of coronary artery stenosis,the number of lesions and the sublingual vein scores;Finally,to analyze the predictive value of sublingual vein scores for CHD.Results1.There were no statistically significant differences in age,gender,overweight,history of hypertension,history of diabetes,dyslipidemia and hyperuricemia between CHD group and non-CHD group(P>0.05),indicating comparability.2.The scores of the thickness,length,distortion,color and texture of the sublingual collation in the CHD group were higher than those in the non-CHD group,and the differences were statistically significant(P<0.05).The score of sublingual vein in CHD group was significantly higher than that in non-CHD group,and the difference was statistically significant(P<0.05).With the increase of sublingual vein scores,the proportion of CHD group was higher and higher,while the proportion of non-CHD group was lower and lower,and the difference was statistically significant(P<0.05).3.The more severe the coronary stenosis,the more the number of coronary lesions,and the higher the sublingual vein scores,the difference was statistically significant(P<0.05).4.The sublingual vein scores in CHD with hypertension and/or diabetes were higher than those in CHD alone,but there was no significant difference in sublingual vein scores among all groups(P>0.05).5.The area under the ROC curve of CHD was 0.744(P<0.05),and when 5 was used as the cut-off point,the sensitivity and specificity were 63.4%and 76.1%.6.Sublingual vein scores higher than 5 points is considered positive,while a sublingual vein scores lower than 5 points is considered negative.For the prediction of CHD,the positive predictive value(PVP)was 71.23%,the negative predictive value(PVP)was 69.07%,the Youden index was 0.396,the positive likelihood ratio(PLIR)was 2.66,the negative likelihood ratio(PLIR)was 0.481,and the odds ratio(OR)was 5.530.ConclusionThe sublingual vein signs are correlated with coronary artery disease,which has certain diagnostic value for CHD in middle aged patients,and may be an effective clinical indication for predicting CHD in middle aged patients with thoracic obstruction.