Study On Preparation And Electrochemical Corrosion Modification Of Graphenene And Its Composite Glucose Sensor

With the progress of society and the improvement of people’s living standard,the number of diabetic patients is increasing day by day.At present,diabetes has become one of the most serious chronic diseases worldwide,causing millions of deaths every year.There is no radical cure for diabetes.Prevention is more important than treatment for diabetes.Early diagnosis of blood glucose plays an important role in the prevention of diabetes.Research on glucose sensors has not been interrupted.In the 21st century,the development of new nanomaterials has greatly improved the performance of electrochemical sensors.Among them,the carbon nanomaterial graphene,with its excellent chemical stability,electrical conductivity,biocompatibility and other properties,has greatly improved the sensitivity,selectivity and linear range of sensors.Electrochemical corrosion as a kind of REDOX reaction,after electrochemical corrosion of metal substrate surface will form a corrosion layer similar to the nanosheet.The surface of the electrode becomes very rough,and these rough surface features can provide more active sites.In this paper,the objective of the construction of electrochemical glucose sensor is to explore its application in the electrochemical sensor by using the nano-material graphene,construct the composite electrochemical glucose sensor,and conduct the modification research of electrochemical corrosion to improve its ability to detect glucose.The main contents are as follows:1,the use of electrochemical way to peel graphene on the graphite,and through the electrochemical corrosion process of the graphene itself to corrode,test the impact of electrochemical corrosion on graphene.Small CVs measured by electrochemical workstation show that electrochemical corrosion of graphene can change the surface morphology of graphene,thus increasing the specific surface area,so as to improve the performance of electrochemical REDOX reaction.2.Strip graphene on the graphite substrate and use it as a carrier to grow copper nanoparticles electrochemically on this basis to form graphite/graphene-copper composites.The addition of copper nanoparticles greatly improves the detection performance of glucose.However,electrodes with copper nanoparticles grown after electrochemical corrosion of graphene and those with copper nanoparticles grown after electrochemical corrosion of graphene have little improvement in the detection performance of glucose,indicating that graphene itself is less affected by electrochemical corrosion.3.Single metal copper-graphene composites were prepared by stripping graphene on copper substrate by electrochemical stripping method.Electrochemical measurements by cyclic voltammetry and chronoamperometry at the Electrochemical Workstation showed that the performance of the monetal-copper graphene composite was significantly improved compared with that of the copper electrode.On a further basis,electrochemical corrosion was used to modify the material.The structure and surface morphology of the material were studied by SEM characterization.It was found that the electrochemical corrosion generated more copper oxides,which was conducive to catalytic oxidation with glucose.Through the electrochemical measurement methods of cyclic voltammetry and chronoamperometry on the electrochemical workstation,it is found that it can achieve stronger performance detection in the detection of glucose.And its impedance spectra were tested.The electrochemical etched samples had lower impedance.4.Cu-Ni graphene composite coating was prepared on copper substrate in graphene powder electroplating solution containing uniformly dispersed nickel salt solution by electrochemical plating process.The bimetallic Cu-Ni electrode was prepared by electrochemical plating process as a control.Through electrochemical measurement,it was found that the Cu-Ni graphene composite coating had improved performance compared with the bimetallic electrode.Then on the basis of electrochemical corrosion modification research,it was found that the electrochemical corrosion of Cu-Ni graphene composite material in the detection of glucose has a more excellent detection performance.