Study On Four Diagnosis Information Of Hypertension Yin Deficiency Syndrome

Objective:Through the clinical epidemiological study,the general information,four diagnostic information and image parameters of newly diagnosed hypertension patients were collected by diagnostic scale,tongue diagnosis,facial diagnosis and pulse diagnosis.The difference between yin deficiency syndrome and non-yin deficiency syndrome of hypertension was analyzed,and the general rules and objective characteristics of four diagnostics were found,which provided reference for dialectical standard study of hypertension yin deficiency syndrome.Methods:(1)Through epidemiological investigation method,92 patients were included.Three TCM experts diagnosed yin deficiency syndrome according to clinical experience,and finally patients were divided into 26 cases of yin deficiency syndrome and 66 cases of non-yin deficiency syndrome.(2)Relevant syndrome factors were collected according to the diagnostic scale of yin deficiency syndrome and the scale of hypertension yin deficiency syndrome.(3)The PSQI and GAD-7 scale were used to evaluate the characteristics of ’less sleep and more dreams’ and’annoyance’ in Yin deficiency syndrome.(4)Collecting quantitative image parameters through tongue,face and pulse diagnostic apparatus.(5)T test,chi-square test,logistic regression,non-parametric test are used to analyze the statistics of four diagnostic information and image parameters.Results:(1)General clinical data:There was no significant difference in course of disease,systolic blood pressure,diastolic blood pressure,heart rate,smoking and drinking between the two groups(P>0.05).There are differences in gender,age,waist circumference and BMI.In Yin deficiency group,age was older and BMI,waist circumference were lower(P≤0.023).Multivariate logistic regression analysis showed that the risk of yin deficiency syndrome increased with age(P=0.047)and decreased with BMI(P=0.022).(2)Scale results:①Diagnostic scale of yin deficiency syndrome:there were significant differences in the symptoms of red tongue and less moss,dysphoria with feverish sensation in chest,palms and soles,sweating,tidal fever at afternoon,thready-rapid pulse,dry mouth and throat,flushed face,dry cough,annoyance and sleeplessness among patients with yin deficiency syndrome(P≤0.022).Red tongue and less moss,dry mouth and throat may be the diagnostic factors of yin deficiency syndrome(P≤0.001).②Diagnostic scale of hypertension yin deficiency syndrome:there were differences in feverishness in palms and soles,dry eyes,thready-string pulse,soreness and weakness of waist and knee,red zygomatic,and tinnitus in patients with yin deficiency syndrome(P≤0.049).Feverishness in palms and soles,dry eyes,thready-string pulse may be the diagnostic factors of hypertension yin deficiency syndrome(P≤0.028).③PSQI and GAD-7 scale:Yin deficiency group had worse sleep quality,PSQI score was higher than that of non-Yin deficiency group(P=0.006).There was no difference in GAD-7 score(P=0.110).(3)Four diagnostic features:①Facial features:red and yellow complexion accounted for a relatively high proportion in yin deficiency(P=0.029),red complexion accounted for a relatively high proportion in non-yin deficiency(P=0.029).There was no significant difference in local features,gloss and lip color(P>0.05).In terms of facial parameters,the "b" value of right cheek color was higher in yin deficiency group(P=0.014).②Tongue features:between the two groups,there was no significant difference in tongue shape,tongue color,local characteristics,coating color and coating quality(P>0.05).On tongue parameters,the "a" value of tongue color(left)was higher in Yin deficiency syndrome(P=0.047).There was no significant difference in the moss parameters(P>0.05).③Pulse features:there was no significant difference in pulse between the two groups(P>0.05).In terms of pulse parameters,h5 and h5/h1 of left hand were significantly lower than those in non-yin deficiency group(P≤0.037),tl/t was higher than that in non-yin deficiency group(P=0.043).t5/t4 of right hand was lower than that in non-yin deficiency group(P=0.047),wl/t was higher than that in non-yin deficiency group(P=0.043).Conclusion:In terms of subjective symptoms,the key symptoms of hypertension yin deficiency syndrome are red tongue and less moss,dry mouth and throat,feverishness in palms and soles,dry eyes,thready-string pulse;In terms of objective characteristics,hypertension yin deficiency syndrome tends to be red and yellow complexion,red tongue and string-week pulse.