| Objective: By comparing "Tong du Tiao zang" acupuncture method with oral sertraline hydrochloride tablet in the treatment of depressive insomnia,the clinical efficacy,effective characteristics and influence on insomnia factors of this method were observed.Methods:72 patients who met the standard of nanogram were divided into treatment group and control group,each group 36 cases.The treatment group was treated with "Tong du Tiao zang" acupuncture method,once a day,and the control group was treated with sertraline hydrochloride tablet once a day.The two groups were treated for one week,a total of 4 courses.Before treatment,the second weekend and the fourth weekend,the Pittsburgh Sleep Quality index scale(PSQI),Hamilton Depression Scale(HAMD),and the control group were treated with sertraline hydrochloride tablet once a day The TPF was evaluated,and the side effects of drugs were observed by Tess,and the adverse reactions of acupuncture were recorded.The data were analyzed by spss22.0 statistical software.Results:1.Observation of curative effect: the effective rates of the treatment group and the control group were 82.35% and 84.84% respectively,which showed no statistical significance after comparison(P>0.05),indicating that there was no significant difference in reducing PSQI score between the two groups.There were significant differences among PSQI,HAMD and TPF groups(P<0.05).Both methods could effectively reduce PSQI and HAMD scores and increase the total sleep time.2.Dynamic aging observation: Comparison of PSQI and HAMD scores at the end of the second week between the groups showed significant difference(P<0.05),indicating that the onset rate of depressive insomnia in the treatment group was better than that in the control group,while the onset rate of depression improvement was slower than that in the control group.At the end of the 4th week,there was a statistically significant difference in total sleep time of TPF between the groups(P<0.05),indicating that the total sleep time of the treatment group was better than that of the control group.3.PSQI factor observation:Compared with the treatment group,the difference was significant(P<0.05),indicating that the treatment group could effectively reduce the scores of each factor;Within the control group,there was no statistically significant difference in hypnotic drugs(P>0.05),and there was statistically significant difference in the remaining 6 factors(P<0.05),indicating that there was no improvement in hypnotic drugs in the control group,but the remaining 6 factors were all improved.At the end of the second week,there were statistically significant differences in sleep quality,sleep time,sleep efficiency and hypnotic drugs between the two groups(P<0.05),indicating that the onset speed of these four factors in the treatment group was better than that in the control group within 2 weeks.At the end of the 4th week,there was statistically significant difference between the groups except for hypnotic drugs(P<0.05),and there was no statistically significant difference between the other 6 factors(P>0.05),indicating that hypnotic drugs improved better than the control group.4.Evaluation of safety and compliance: During the trial,no serious adverse events occurred in patients of the two groups,and 15 patients with mild adverse reactions insisted on continuing to participate in the treatment.The safety and compliance of the two groups were good.Conclusion:1.Both the "Tong du Tiao zang" acupuncture method and the oral sertraline hydrochloride tablet can effectively treat depressive insomnia,reduce HAMD and PSQI scores,and increase the total sleep time,with no significant difference in efficacy.2.The effective rate of "Tong du Tiao zang" acupuncture in the treatment of depressive insomnia is faster than that of oral sertraline hydrochloride tablets,especially in the sleep quality,sleep time,sleep efficiency and hypnotic drugs,and the improvement is more comprehensive,but the effective rate of depression improvement is slower than that of oral sertraline hydrochloride tablets.3.The treatment of depressive insomnia with "Tong du Tiao zang" acupuncture is better than oral sertraline hydrochloride tablets in improving the total sleep time. |
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