Analysis Of Clinical Characteristics And Related Risk Factors Of Poor Prognosis In Elderly Patients With Chronic Coronary Syndrome

Objective:To investigate the clinical characteristics of chronic coronary syndrome(CCS)patients in the elderly,and the analysis of related risk factors for poor prognosis after revascularization,and to provide relevant information for the prevention and treatment of chronic coronary syndromes in the elderly in accordance with.Methods:268 patients who were diagnosed with chronic coronary syndrome and who had undergone revascularization,namely percutaneous coronary stent implantation(PCI),were selected from September 2018 to September 2019 in the cardiology department of Subei people’s hospital.Cases,and the collection,collection and sorting of corresponding data for such patients.Record the patient’s angiographic results:the number of diseased branches;adverse cardiovascular events:recurrence or exacerbation of angina,acute myocardial infarction,severe arrhythmia,heart failure,revascularization.The patients were followed up for 1 year through telephone,outpatient service,etc.The data obtained from it is analyzed in detail.The software used for the analysis is SPSS23.0 statistical software,in which the range of the difference between the upper and lower standard deviation values??of the average value is used to represent the measurement data,and the t-test method is adopted,andχ~2-test method compares the count data,and uses the multivariate Logistic regression method to analyze the independent risk factors of poor prognosis after PCI for chronic coronary syndrome.Statistics that simultaneously satisfy the contrast and difference with P<0.05 are considered statistically significant.Results:1.A total of 268 patients were enrolled in this study.The oldest was 89 years old and the youngest was 60 years old.The patients were divided into two groups according to their age.Group A was 60～74 years old(140 cases),and Group B was75～89 years old(128 cases).The differences in hypertension,hyperlipidemia,and diabetes between the two groups were statistically significant(P<0.05).The two groups were in gender,BMI,history of atrial fibrillation,history of cerebral infarction,history of smoking,history of drinking,medication status,RBC,Hb,WBC,PLT,ALT,AST,TC,TG,LDL,HDL,GLU,HBA1c,NT-pro BNP,Tn I,CK-MB,Cr,UA,and BUN There was no significant difference(P>0.05).2.Comparing the number of coronary artery disease in patients of different age groups,the prevalence of single-vessel coronary artery disease in group A is higher than that in group B,and the prevalence of multi-vessel coronary artery disease is significantly lower than that in group B,and the differences are statistically significant(P<0.05).However,there was no statistically significant difference in double-vessel disease between the two groups(P>0.05).3.During the 12 month follow-up period,64 cases(23.88%)had adverse cardiovascular events,38 cases of recurrence or exacerbation of central colic,10 cases of acute myocardial infarction,3 cases of severe arrhythmia,5 cases of heart failure,and revascularization 8 cases were reconstructed.In addition,the incidence of adverse cardiovascular events in group B patients aged 75～89 years was significantly higher than that in group A patients aged 60～74 years,and the difference between the two groups was statistically significant(P<0.05).4.According to the follow-up results,whether the patients had adverse cardiovascular events after PCI were divided into a good prognosis group and a poor prognosis group.The comparison between the two groups showed that the age distribution of patients in the poor prognosis group was 75～89 years old,and the rates of patients with hypertension,hyperlipidemia,diabetes,and smoking history were significantly higher than those in the good prognosis group(P<0.05),But in terms of gender,BMI,history of atrial fibrillation,history of cerebral infarction,history of drinking,RBC,Hb,WBC,PLT,ALT,AST,TC,TG,LDL,HDL,GLU,HBA1c,NT-pro BNP,Tn I,CK-MB,Cr,UA,BUN,There were no statistically significant differences and the number of lesions(P>0.05).Among patients in the poor prognosis group,β-blockers accounted for a lower proportion,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the consumption of other drugs between the two groups(P>0.05).5.The results of multivariate logistic regression analysis showed that aged 75～89 years(OR=1.12),with hypertension(OR=2.57),with diabetes(OR=1.31),with hyperlipidemia(OR=1.62),smoking History(OR=1.02)and oralβ-blockers(OR=0.34)are independent risk factors for adverse cardiovascular events in elderly patients with chronic coronary syndrome(P<0.05).Conclusion:1.Elderly patients with chronic coronary syndromes aged 75-89 have more underlying diseases than those aged 60-74 years,most of whom have diabetes,hypertension,and hyperlipidemia;the proportion of coronary artery multivessel disease is higher;The proportion of adverse cardiovascular events after PCI is higher,and the prevention and screening of elderly chronic coronary syndromes should be strengthened in clinical work.2.Age,hypertension,hyperlipidemia,diabetes,and smoking may be risk factors for adverse cardiovascular events in elderly patients with chronic coronary syndromes within 1 year after PCI,andβ-blockers may be protective factors.