| Objective: To observe the effect of gestational diabetes on neonatal blood glucose level and related complications,so as to avoid the occurrence of neonatal complications,and to provide reference for the clinical management of neonatal mothers with gestational diabetes.Method:1.A total of 105 neonates delivered by GDM mothers in the neonatal follow-up clinic of the First People’s Hospital of Yunnan Province from June 2019 to June 2020 were collected as the GDM group,and 105 neonates delivered by non-GDM pregnant women were randomly selected as the control group(non-GDM group).The blood glucose values of neonates at 1h,12 h,24h and 48 h after birth and the control values were analyzed.At the same time,the incidence of neonatal complications in the two groups was statistically analyzed and studied.2.According to the body weight and gestational age of the newborns,the GDM group was divided into the gestational age group(LGA,A1 group)and the gestational age non-gestational age group(including the gestational age group and the school-age group)(SGA/AGA,A2 group),and the incidence of complications in the two groups was compared.3.Echocardiography was performed within 1 week after birth in the two groups of neonates to observe their aorta,left atrium,right ventricle septum and other heart-related indicators,and statistical analysis was conducted.Result:1.The total number of hypoglycemia in the GDM group was 17 cases,accounting for 16.19%(17/105),and the total number of hypoglycemia in the control group was 7cases,accounting for 6.7%(7/105).Comparing the blood glucose value of neonates one hour after birth with that of the control group,the difference between the two groups was statistically significant(P < 0.05).The blood glucose values at 12,24 and 48 hours after birth were compared with the control group,and there was no statistical significance between the two groups(P > 0.05).Neonatal complications in GDM group included hypoglycemia,older than gestational age,neonatal asphyxia,neonatal birth injury,malformation,neonatal hyperbilirubinemia,and so on,and the differences were statistically significant(P < 0.05).2.It was found that the occurrence rate of neonatal hypoglycemia in A1 group was36.3%,and that in A2 group was 13.8%,both of which were higher in A1 group than in A2 group,with statistical significance(P < 0.05).There was no statistical significance in the complications of childbirth injury,malformation,neonatal hyperbilirubinemia,asphyxia and other complications between the two groups(P > 0.05).3.Compared with the control group,the measures of ventricular septum and other heart-related indexes in the GDM group were all higher than those in the control group,with statistical significance(P < 0.05).In the case of no difference in body weight between the two groups,the thickness of interventr ICULAR septum in the GDM group was greater than that in the control group,and the difference was statistically significant(P < 0.05),while other indicators were not statistically significant(P > 0.05).Conclusion:1.Neonates born to mothers with gestational diabetes mellitus are prone to hypoglycemia,which usually occurs within 1 hour after birth.Infants older than gestational age are more prone to hypoglycemia.2.Gestational diabetes can not only cause of neonatal hypoglycemia state,also can increase neonatal respiratory distress,is greater than the gestational age,deformity,high neonatal bilirubin levels,complications;3.The mother of gestational diabetes mellitus has significant adverse effects on neonatal heart development,especially the interventricular septum thickness increases,However,its pathogenesis and prevention still need further research. |
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